Mastocytosis is one of eight subcategories of myeloproliferative neoplasms (MPN) according to the World Health Organization (WHO) «classification of tumors of hematopoietic and lymphoid tissues» (2008). Mastocytosis is a ...

Bakgrunn: Naturlige drepeceller tilhører en gruppe medfødte lymfocytter som spiller viktige roller i eliminering av kreft og virusinfiserte celler. Målsettingen: Målet med oppgaven var å se hvilke mekanismer naturlige ...

Celiac disease (CD) is a chronic small intestinal inflammation driven by an immune response to gluten peptides in genetically susceptible individuals. CD was considered as a childhood disease for a long time, but the ...

Syklisk nøytropeni er en sjelden, autosomal dominant sykdom. Den er karakterisert av lave nivåer av nøytrofile granulocytter ned til under 0,5 x 10 9/L hver tredje uke. Symptomer er vanligvis after, feber og til tider ...

The RhD antigen is clinically the most important human blood group antigen involved in hemolytic disease of the newborn (HDN). Immunization against the human platelet antigen (HPA)-1a is the most common cause of neonatal ...

Abstract Introduction. Antisynthetase syndrome (ASS) is a clinical entity recognized as the combination of auto-antibodies against an amino-acyl-tRNA synthetase and interstitial lung disease. Usually the patients also ...

Abstract The purpose of this study was to review the literature concerning how physical strain among elite athletes in endurance sports influences their immune system. By literature search in Pubmed, I have studied exercise ...

Celiac disease is a chronic inflammatory disease induced by ingested gluten from wheat, and similar proteins from barley and rye. An inappropriate immune response to gluten peptides leads to lymphocyte infiltration, villous ...

Increased levels of the Th2-associated leukotriene C4 (LTC4) have been described in celiac disease. LTC4 is mainly produced by LTC4-synthase containing mast cells and eosinophils in a Th2 cytokine (IL-4, IL-5) depended ...

Abstract: The purpose of this study was to review results on exercise induced changes in the immune system during and after strenuous long term exercise in athletes and well-trained individuals. By performing a literature ...

Abstract Mesenchymal stem cells (MSC), found in the bone-marrow, the blood circulation, adipose tissue and fetal lungs, have recently been subject to great interest from researchers and clinicians worldwide. These cells ...

Lymfomer er en heterogen malign sykdomsgruppe med utspring fra B og T-celler i immunsystemet. Cellene har reseptorer for en rekke cytokiner, som under normale forhold regulerer deres vekst og differensiering. En kan anta ...

Louka AS, Stensby EK, Ek J, Gudjónsdóttir AH, Ascher H, Sollid LM. Coeliac disease candidate genes: No association with functional polymorphisms in matrix metalloproteinase 1 and 3 gene promoters. Scand J Gastroentero l ...

The SH2D2A gene codes for a protein which was named T cell specific adapter protein (TSAd) by the group who cloned it in 1997. The gene is located to 1q21, a region where several immunoregulative genes are situated. The ...

Microchimerism may play a part in transfusion complications. The aim of this study was to see if the establishment of post transfusion microchimerism was dose dependent. Methods: Twenty non-pregnant female patients, without ...

This project is about a theoretical model for development of autoimmune disease. The central point in this model is idiotype (Id) dependent T and B cell cooperation. B cells with idiotype sequence in their antibody (Id+ B ...

The proliferation, differentiation and maturation of haematopoietic progenitor cells into megakaryocytic progenitors in vitro, is dependant upon the growth factors. To establish what growth factors give the highest expansion ...