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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background: In precision cancer medicine, the challenge is to prioritize DNA driver events, account for resistance markers, and procure sufficient information for treatment that maintains patient safety. The MetAction ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Somatic copy number alterations are a frequent sign of genome instability in cancer. A precise characterization of the genome architecture would reveal underlying instability mechanisms and provide an instrument for outcome ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Targeted therapy for patients with HER2‐positive (HER2+) breast cancer has improved overall survival, but many patients still suffer relapse and death from the disease. Intratumor heterogeneity of both estrogen receptor ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Objective Through the conduct of an individual-based intervention study, the main purpose of this project was to build and evaluate the required infrastructure that may enable routine practice of precision cancer medicine ...