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MicroJam: An App for Sharing Tiny Touch-Screen Performances 
Martin, Charles Patrick; Tørresen, Jim (Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2017)
MicroJam is a mobile app for sharing tiny touch-screen performances. Mobile applications that streamline creativity and social interaction have enabled a very broad audience to develop their own creative practices. While ...
NucDiff: in-depth characterization and annotation of differences between two sets of DNA sequences 
Khelik, Ksenia; Lagesen, Karin; Sandve, Geir K; Rognes, Torbjørn; Nederbragt, Alexander J (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background Comparing sets of sequences is a situation frequently encountered in bioinformatics, examples being comparing an assembly to a reference genome, or two genomes to each other. The purpose of the ...
Visions of Illness, Disease, and Sickness in Mobile Health Applications 
Sommervold, Margaret Machniak; van der Velden, Maja (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Popular media and public health care discourses describe an increasing number of mobile health technologies. These applications tend to be presented as a means of achieving patient empowerment, patient-centered care, and ...
Security Classification for Smart Grid Infra structures (long version) 
Shrestha, Manish; Johansen, Christian; Noll, Josef (Research report / PublishedVersion; Peer reviewed, 2017)
The present report proposes a methodology for Smart Grid Security Classification (SGSC) having as target usage the complex systems in the smart grids and particularly Advanced Metering Infrastructures (AMI). Our methodology ...
Efficient verification of railway infrastructure designs against standard regulations 
Luteberget, Bjørnar Steinnes; Johansen, Christian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
In designing safety-critical infrastructures s.a. railway systems, engineers often have to deal with complex and large-scale designs. Formal methods can play an important role in helping automate various tasks. For railway ...
Differential Expression and Cell-Type Specificity of Perineuronal Nets in Hippocampus, Medial Entorhinal Cortex and Visual Cortex Examined in the Rat and Mouse 
Lensjø, Kristian Kinden; Christensen, Ane Charlotte; Tennøe, Simen; Fyhn, Marianne; Hafting, Torkel (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Perineuronal nets (PNNs) are specialized extracellular matrix (ECM) structures that condense around the soma and proximal dendrites of subpopulations of neurons. Emerging evidence suggests that they are involved in regulating ...
Prognostic and diagnostic significance of copeptin in acute exacerbation of chronic obstructive pulmonary disease and acute heart failure: data from the ACE 2 study 
Winther, Jacob A; Brynildsen, Jon; Høiseth, Arne D; Strand, Heidi; Følling, Ivar; Christensen, Geir; Nygård, Ståle; Røsjø, Helge; Omland, Torbjørn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background Copeptin is a novel biomarker that predicts mortality in lower respiratory tract infections and heart failure (HF), but the diagnostic value of copeptin in acute dyspnea and the prognostic ...
Data Leakage Prevention for Secure Cross-Domain Information Exchange 
Kongsgård, Kyrre Wahl; Nordbotten, Nils Agne; Mancini, Federico; Haakseth, Raymond; Engelstad, Paal E. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Cross-domain information exchange is an increasingly important capability for conducting efficient and secure operations, both within coalitions and within single nations. A data guard is a common cross-domain sharing ...
The longitudinal transcriptional response to neoadjuvant chemotherapy with and without bevacizumab in breast cancer 
Silwal-Pandit, Laxmi; Nord, Silje; Gythfeldt, Hedda; Møller, Elen Kristine; Fleischer, Thomas; Rødland, Einar Andreas; Krohn, Marit; Borgen, Elin; Garred, Øystein; Olsen, Tone; Vu, Phuong Ngoc Thi; Skjerven, Helle; Fangberget, Anne; Holmen, Marit Muri; Schlichting, Ellen; Wille, Elisabeth; Stokke, Mette Norberg; Vollan, Hans Kristian Moen; Kristensen, Vessela N.; Langerød, Anita; Lundgren, Steinar; Wist, Erik; Naume, Bjørn; Lingjærde, Ole Christian; Børresen-Dale, Anne-Lise; Engebråten, Olav (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Purpose: Chemotherapy-induced alterations to gene expression are due to transcriptional reprogramming of tumor cells or subclonal adaptations to treatment. The effect on whole-transcriptome mRNA expression was investigated ...
Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report 
Seppälä, Toni; Pylvänäinen, Kirsi; Evans, Dafydd G; Järvinen, Heikki; Renkonen-Sinisalo, Laura; Bernstein, Inge; Holinski-Feder, Elke; Sala, Paola; Lindblom, Annika; Macrae, Finlay; Blanco, Ignacio; Sijmons, Rolf; Jeffries, Jacqueline; Vasen, Hans; Burn, John; Nakken, Sigve; Hovig, Eivind; Rødland, Einar A; Tharmaratnam, Kukatharmini; de Vos tot Nederveen Cappel, Wouter H; Hill, James; Wijnen, Juul; Jenkins, Mark; Genuardi, Maurizio; Green, Kate; Lalloo, Fiona; Sunde, Lone; Mints, Miriam; Bertario, Lucio; Pineda, Marta; Navarro, Matilde; Morak, Monika; Frayling, Ian M; Plazzer, John-Paul; Sampson, Julian R; Capella, Gabriel; Möslein, Gabriela; Mecklin, Jukka-Pekka; Møller, Pål (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background We have previously reported a high incidence of colorectal cancer (CRC) in carriers of pathogenic MLH1 variants (path_MLH1) despite follow-up with colonoscopy including polypectomy. ...
Tracing armed conflicts with diachronic word embedding models 
Kutuzov, Andrei; Velldal, Erik; Øvrelid, Lilja (Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2017)
Recent studies have shown that word embedding models can be used to trace time-related (diachronic) semantic shifts for particular words. In this paper, we evaluate some of these approaches on the new task of predicting ...
Exploring Social Mobile Music with Tiny Touch-Screen Performances 
Martin, Charles Patrick; Tørresen, Jim (Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2017)
Touch-screen musical performance has become commonplace since the widespread adoption of mobile devices such as smartphones and tablets. However, mobile digital musical instruments are rarely designed to emphasise collaborative ...
Operational Semantics of a Weak Memory Model inspired by Go 
Fava, Daniel Schnetzer; Stolz, Volker; Valle, Stian (Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2017)
A memory model dictates which values may be returned when reading from memory. In a parallel computing setting, the memory model affects how processes communicate through shared memory. The design of a proper memory model ...
Analysis of Lamarckian Evolution in Morphologically Evolving Robots 
Jelisavcic, Milan; Kiesel, Rafael; Glette, Kyrre; Haasdijk, Evert; Eiben, AE (Chapter / Bokkapittel / AcceptedVersion; Peer reviewed, 2017)
Evolving robot morphologies implies the need for lifetime learning so that newborn robots can learn to manipulate their bodies. An individual’s morphology will obviously combine traits of all its parents; it must adapt its ...
An Evaluation of Score Level Fusion Approaches for Fingerprint and Finger-vein Biometrics 
Vishi, Kamer; Mavroeidis, Vasileios (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Biometric systems have to address many requirements, such as large population coverage, demographic diversity, varied deployment environment, as well as practical aspects like performance and spoofing attacks. Traditional ...
Temporal dynamics of semantic relations in word embeddings: an application to predicting armed conflict participants 
Kutuzov, Andrei; Velldal, Erik; Øvrelid, Lilja (Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2017)
This paper deals with using word embedding models to trace the temporal dynamics of semantic relations between pairs of words. The set-up is similar to the well-known analogies task, but expanded with a time dimension. To ...
Robust Real-Time Needle Tracking in 2-D Ultrasound Images Using Statistical Filtering 
Mathiassen, Kim; Dall’Alba, Diego; Muradore, Riccardo; Fiorini, Paolo; Elle, Ole Jakob (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Percutaneous image-guided tumor ablation is a minimally invasive surgical procedure for the treatment of malignant tumors using a needle-shaped ablation probe. Automating the insertion of a needle by using a robot could ...
High-Performance Computation of Bézier Surfaces on Parallel and Heterogeneous Platforms 
Palomar, Rafael; Gómez-Luna, Juan; Alaya Cheikh, Faouzi; Olivares-Bueno, Joaquín; Elle, Ole Jakob (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Bézier surfaces are mathematical tools employed in a wide variety of applications. Some works in the literature propose parallelization strategies to improve performance for the computation of Bézier surfaces. These ...
Comparing Implementations of Secure Messaging Protocols (long version) 
Johansen, Christian; Mujaj, Aulon; Arshad, Hamed; Noll, Josef (Research report / Forskningsrapport / PublishedVersion; Peer reviewed, 2017)
In recent years, it has come to attention that governments have been doing mass surveillance of personal communications without the consent of the citizens. As a consequence of these revelations, developers have begun ...
An improved genome assembly uncovers prolific tandem repeats in Atlantic cod 
Tørresen, Ole K; Star, Bastiaan; Jentoft, Sissel; Reinar, William B; Grove, Harald; Miller, Jason R; Walenz, Brian P; Knight, James; Ekholm, Jenny M; Peluso, Paul; Edvardsen, Rolf B; Tooming-Klunderud, Ave; Skage, Morten; Lien, Sigbjørn; Jakobsen, Kjetill S; Nederbragt, Alexander J (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background The first Atlantic cod (Gadus morhua) genome assembly published in 2011 was one of the early genome assemblies exclusively based on high-throughput 454 pyrosequencing. Since then, rapid advances ...
Robust Cross-Platform Workflows: How Technical and Scientific Communities Collaborate to Develop, Test and Share Best Practices for Data Analysis 
Möller, Steffen; Prescott, Stuart W.; Wirzenius, Lars; Reinholdtsen, Petter; Chapman, Brad; Prins, Pjotr; Soiland-Reyes, Stian; Klötzl, Fabian; Bagnacani, Andrea; Kalaš, Matúš; Tille, Andreas; Crusoe, Michael R. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Information integration and workflow technologies for data analysis have always been major fields of investigation in bioinformatics. A range of popular workflow suites are available to support analyses in computational ...
T cells expressing checkpoint receptor TIGIT are enriched in follicular lymphoma tumors and characterized by reversible suppression of T-cell receptor signaling 
Josefsson, Sarah Elisabet Göthberg; Huse, Kanutte; Kolstad, Arne; Beiske, Klaus; Pende, Daniela; Steen, Chloe Beate; Inderberg, Else Marit; Lingjærde, Ole Christian; Østenstad, Bjørn; Smeland, Erlend B; Levy, Ronald; Irish, Jonathan M.; Myklebust, June (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Purpose: T cells infiltrating follicular lymphoma (FL) tumors are considered dysfunctional, yet the optimal target for immune checkpoint blockade is unknown. Characterizing coinhibitory receptor expression patterns and ...
NEAT: A Platform- and Protocol-Independent Internet Transport API 
Khademi, Naeem; Ros, David; Welzl, Michael; Bozakov, Zdravko; Brunstrom, Anna; Fairhurst, Gorry; Grinnemo, Karl-Johan; Hayes, David; Hurtig, Per; Jones, Tom; Mangiante, Simone; Tüxen, Michael; Weinrank, Felix (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
The sockets API has become the standard way that applications access the transport services offered by the IP stack. This article presents NEAT, a user space library that can provide an alternate transport API. NEAT allows ...
Fast and robust common-reflection-surface parameter estimation 
Waldeland, Anders Ueland; Zhao, Hao; Faccipieri, J. H.; Solberg, Anne H Schistad; Gelius, Leiv-J. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
The common-reflection-surface (CRS) method offers a stack with higher signal-to-noise ratio at the cost of a time-consuming semblance search to obtain the stacking parameters. We have developed a fast method for extracting ...
Smart environments? Reflections on the role of metaphors in IS 
Geirbo, Hanne Cecilie (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Our cities, landscapes, institutions, and homes are increasingly being equipped with sensors that glean information that is being processed by algorithms and visualized to serve as a basis for decision making. Such Internet ...
Overcoming initial convergence in multi-objective evolution of robot control and morphology using a two-phase approach 
Nygaard, Tønnes Frostad; Samuelsen, Eivind; Glette, Kyrre (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Co-evolution of robot morphologies and control systems is a new and interesting approach for robotic design. However, the increased size and ruggedness of the search space becomes a challenge, often leading to early ...
Individuell "automagisk" tilbakemelding på skriftlig eksamen 
Mirmotahari, Omid; Berg, Yngvar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
I denne artikkelen viser vi et nytt system for å kunne gi delvis automatisk og formativ tilbakemelding til studenter på skriftlig eksamen. Vi vil belyse en ny måte å gi individuell tilbakemelding rettet mot hver enkelt ...
Innovation in the fringes of software ecosystems: the role of socio-technical generativity 
Msiska, Brown Chawanangwa; Nielsen, Petter (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Understanding the way information systems grow and change over time and the role of different contributors in these processes is central to current research on software development and innovation. In relation to this, there ...
A stable non-interleaving early operational semantics for the Pi-calculus 
Hildebrandt, Thomas; Johansen, Christian; Normann, Håkon (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
We give the first non-interleaving early operational semantics for the pi-calculus which generalizes the standard interleaving semantics and unfolds to the stable model of prime event structures. Our starting point is the ...
A Governance Model for Managing Lightweight IT 
Bygstad, Bendik; Iden, Jon (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
The widespread introduction of lightweight IT—smartphones, tablets, the Internet of Things, and the growth of third-party app developers—has become a challenge for many organizations. Local units and end-users increasingly ...
A Fault-Tolerant Routing Strategy for K-ary N-direct S-indirect Topologies Based on Intermediate Nodes 
Peñaranda, Roberto; Lopez, Pedro; Gómez, Maria E.; Gran, Ernst Gunnar; Skeie, Tor (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Exascale computing systems are being built with thousands of nodes. The high number of components of these systems significantly increases the probability of failure. A key component for them is the interconnection network. ...
Participatory verification of railway infrastructure by representing regulations in RailCNL 
Luteberget, Bjørnar Steinnes; Camilleri, John J.; Johansen, Christian; Schneider, Gerardo (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Designs of railway infrastructure (tracks, signalling and control systems, etc.) need to comply with comprehensive sets of regulations describing safety requirements, engineering conventions, and design heuristics. We have ...
Participatory Continuing Design: “Living with” Videoconferencing in Rehabilitation 
Aanestad, Margunn; Driveklepp, Anne Merete; Sørli, Hilde; Hertzum, Morten (Chapter / Bokkapittel / AcceptedVersion; Peer reviewed, 2017)
While much research emphasizes design-before-use, we here study design-in-use. The notion of participatory continuing design is introduced to draw attention to the ongoing work of incorporating information and communication ...
A Cost-Benefit Analysis of Accessibility Testing in Agile Software Development: Results from a Multiple Case Study 
Bai, Aleksander; Mork, Heidi Camilla; Stray, Viktoria (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
It is important to include accessibility testing in software development to ensure that the software developed is usable by as many people as possible, independent of their capabilities. Few guidelines exist on how to ...
An evaluation of the accuracy of classical models for computing the membrane potential and extracellular potential for neurons 
Tveito, Aslak; Jæger, Karoline Horgmo; Lines, Glenn Terje; Paszkowski, Lukasz; Sundnes, Joakim; Edwards, Andrew; Mäki-Marttunen, Tuomo; Halnes, Geir; Einevoll, Gaute (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Two mathematical models are part of the foundation of Computational neurophysiology; (a) the Cable equation is used to compute the membrane potential of neurons, and, (b) volume-conductor theory describes the extracellular ...
fling: A Flexible Ping for Middlebox Measurements 
Barik, Runa; Welzl, Michael; Elmokashfi, Ahmed Mustafa Abdalla; Gjessing, Stein; Islam, Safiqul (Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2017)
Middleboxes in private networks have been known to change packets in many ways, making it hard to design protocol extensions that work for the large majority of Internet users. Addressing the need to know what such middleboxes ...
De-Ossifying the Internet Transport Layer: A Survey and Future Perspectives 
Papastergiou, Giorgos; Fairhurst, Gorry; Ros, David; Brunstrom, Anna; Grinnemo, Karl-Johan; Hurtig, Per; Khademi, Naeem; Tüxen, Michael; Welzl, Michael; Damjanovic, Dragana; Mangiante, Simone (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
It is widely recognized that the Internet transport layer has become ossified, where further evolution has become hard or even impossible. This is a direct consequence of the ubiquitous deployment of middleboxes that hamper ...
Are Daily Stand-up Meetings Valuable? A Survey of Developers in Software Teams 
Stray, Viktoria; Moe, Nils Brede; Bergersen, Gunnar R. (Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2017)
The daily stand-up meeting is a widely used practice. However, what is more uncertain is how valuable the practice is to team members. We invited professional developers of a programming forum to a survey and obtained 221 ...
Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate 
Ree, Anne Hansen; Russnes, Hege Elisabeth Giercksky; Heinrich, Daniel; Dueland, Svein; Pedersen, Kjetil Boye; Nygaard, Vigdis; Silwal-Pandit, Laxmi; Østrup, Olga; Hovig, Eivind; Nygaard, Vegard; Rødland, Einar Andreas; Nakken, Sigve; Øien, Janne T; Johansen, Christin; Bergheim, Inger; Skarpeteig, Veronica; Sathermugathevan, Menaka; Sauer, Torill; Lund-Iversen, Marius; Beiske, Klaus; Nasser, Salah; Julsrud, Lars; Reisse, Claudius; Ruud, Espen Asak; Flørenes, Vivi Ann; Hagene, Kirsten T; Aas, Eline; Lurås, Hilde; Soriano, Siv Johnsen; Geitvik, Gry Aarum; Lingjærde, Ole Christian; Børresen-Dale, Anne-Lise; Mælandsmo, Gunhild; Flatmark, Kjersti (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Objective Through the conduct of an individual-based intervention study, the main purpose of this project was to build and evaluate the required infrastructure that may enable routine practice of precision cancer medicine ...
Reasonable Macros for Ontology Construction and Maintenance 
Forssell, Jon Henrik; Lupp, Daniel Paul; Skjæveland, Martin G; Thorstensen, Evgenij (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Reasonable Ontology Templates, OTTRs for short, are OWL ontology macros capable of representing ontology design patterns (ODPs) and closely integrating their use into ontology engineering. An OTTR is itself an OWL ontology ...
Generative innovation: a comparison of lightweight and heavyweight IT 
Bygstad, Bendik (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
This paper proposes a simple terminology for understanding and dealing with two current phenomena; we suggest calling them heavyweight and lightweight IT. Heavyweight IT denotes the well-established knowledge regime of ...
Modelling of the Acoustic Radiation Force in elastography 
Prieur, Fabrice Jean Gabriel; Sapozhnikov, Oleg (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Copyright (2017) Acoustical Society of America. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the Acoustical Society of America. The following article ...
Localizing neuronal somata from Multi-Electrode Array in-vivo recordings using deep learning 
Buccino, Alessio Paolo; Ness, Torbjørn Vefferstad; Einevoll, Gaute; Cauwenberghs, Gert; Häfliger, Philipp (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
With the latest development in the design and fabrication of high-density Multi-Electrode Arrays (MEA) for in-vivo neural recordings, the spatiotemporal information in the recorded signals allows for refined estimation of ...
Process Innovation Meeets Digital Infrastructure in a High-Tech Hospital 
Bygstad, Bendik; Hanseth, Ole; Siebenherz, Anette; Øvrelid, Egil (Chapter / Bokkapittel / AcceptedVersion; Peer reviewed, 2017)
Digitalisation is usually about process innovation with the use of IT, i.e. automating or informating organisational processes. However, redesigned processes are often misaligned with the underlying digital infrastructure. ...
Point scatterer enhancement in ultrasound by wavelet coefficient shrinkage 
Hverven, Stine Myhre; Rindal, Ole Marius Hoel; Hunter, Alan J.; Austeng, Andreas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background speckle can often obscure objects of interest in an ultrasound image. The probability of detection and classification of point scatterers is highly affected by background speckle. The proposed algorithm uses a ...
Joint UD Parsing of Norwegian Bokmål and Nynorsk 
Velldal, Erik; Øvrelid, Lilja; Hohle, Petter (Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2017)
This paper investigates interactions in parser performance for the two official standards for written Norwegian: Bokmål and Nynorsk. We demonstrate that while applying models across standards yields poor performance, ...
Fractional biharmonic operator equation model for arbitrary frequency-dependent scattering attenuation in acoustic wave propagation 
Chen, Wen; Fang, Jun; Pang, Guofei; Holm, Sverre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
This paper proposes a fractional biharmonic operator equation model in the time-space domain to describe scattering attenuation of acoustic waves in heterogeneous media. Compared with the existing models, the proposed ...
An MDE Approach for Modelling and Reasoning about Multi-agent Systems 
Rabbi, Fazle; Lamo, Yngve; Kristensen, Lars Michael (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
Epistemic logic plays an important role in artificial intelligence for reasoning about multi-agent systems. Current approaches for modelling multi-agent systems with epistemic logic use Kripke semantics where the knowledge ...
High number of kinome-mutations in non-small cell lung cancer is associated with reduced immune response and poor relapse-free survival 
Helland, Å; Brustugun, O.T; Nakken, S; Halvorsen, A.R; Dønnem, Tom; Bremnes, R.; Busund, Lill-Tove; Sun, J; Lorenz, S; Solberg, S; Jørgensen, LH; Vodak, Daniel; Myklebost, Ola; Hovig, Eivind; Meza-Zepeda, Leonardo A (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Lung cancer is the leading cause of cancer related death, and the past years’ improved insight into underlying molecular events has significantly improved outcome for specific subsets of patients. In particular, several ...
Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG 
Alsøe, Lene; Sarno, Antonio; Carracedo Huroz, Sergio; Domanska, Diana Ewa; Dingler, Felix; Lirussi, Lisa; Sengupta, Tanima; Tekin, Nuriye Basdag; Jobert, Laure; Alexandrov, Ludmil B.; Galashevskaya, Anastasia; Rada, Cristina; Sandve, Geir Kjetil; Rognes, Torbjørn; Krokan, Hans Einar; Nilsen, Hilde Loge (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Both a DNA lesion and an intermediate for antibody maturation, uracil is primarily processed by base excision repair (BER), either initiated by uracil-DNA glycosylase (UNG) or by single-strand selective monofunctional ...
DCEP-Sim: An Open Simulation Framework for Distributed CEP 
Starks, Fabrice; Kristiansen, Stein; Plagemann, Thomas Peter (Chapter / Bokkapittel / AcceptedVersion; Peer reviewed, 2017)
Distributed Complex Event Processing (CEP) is gaining increasing interest for two reasons: (1) to scale system performance to handle higher workloads in real-time, and (2) to perform in-network processing, e.g., in mobile ...
The UltraSound ToolBox 
Rodriguez-Molares, Alfonso; Rindal, Ole Marius Hoel; Bernard, Olivier; Nair, Arun; Bell, Muyinatu A. Lediju; Liebgott, Herve; Austeng, Andreas; Løvstakken, Lasse (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
We present the UltraSound ToolBox (USTB), a processing framework for ultrasound signals. USTB aims to facilitate the comparison of imaging techniques and the dissemination of research results. It fills the void of tools ...
Optimizing Distributed Resource Allocation using Epistemic Game Theory: A Model-driven Engineering Approach 
Rabbi, Fazle; Kristensen, Lars Michael; Lamo, Yngve (Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2017)
Abstract: Distributed systems modelling often involves a set of heterogeneous models where each model specifies a set of local constraints capturing a specific view of the system. In real life, distributed systems are often ...
HPV Genotyping of Modified General Primer-Amplicons Is More Analytically Sensitive and Specific by Sequencing than by Hybridization 
Meisal, Roger; Rounge, Trine Ballestad; Christiansen, Irene Kraus; Eieland, Alexander Kirkeby; Worren, Merete Molton; Molden, Tor; Kommedal, Øyvind; Hovig, Eivind; Leegaard, Truls Michael; Ambur, Ole Herman (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Sensitive and specific genotyping of human papillomaviruses (HPVs) is important for population-based surveillance of carcinogenic HPV types and for monitoring vaccine effectiveness. Here we compare HPV genotyping by Next ...
Wordnet extension via word embeddings: Experiments on the Norwegian Wordnet 
Sand, Heidi; Velldal, Erik; Øvrelid, Lilja (Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2017)
This paper describes the process of automatically adding synsets and hypernymy relations to an existing wordnet based on word embeddings computed for POStagged lemmas in a large news corpus, achieving exact match attachment ...
Optimizing a PoS Tagset for Norwegian Dependency Parsing 
Hohle, Petter; Øvrelid, Lilja; Velldal, Erik (Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2017)
This paper reports on a suite of experiments that evaluates how the linguistic granularity of part-of-speech tagsets impacts the performance of tagging and syntactic dependency parsing. Our results show that parsing accuracy ...
Re-Infrastructuring for eHealth: Dealing with Turns in Infrastructure Development 
Grisot, Miria; Vassilakopoulou, Polyxeni (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
In this paper, we examine infrastructuring in the context of developing national, public eHealth services in Norway. Specifically, we analyze the work of a project team engaged in the design and development of new web-based ...
Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: A report from the prospective Lynch syndrome database 
Møller, Pål; Seppälä, Toni; Bernstein, Inge; Holinski-Feder, Elke; Sala, Paola; Evans, D. Gareth; Lindblom, Annika; MacRae, Finlay; Blanco, Ignacio; Sijmons, Rolf; Jeffries, Jacqueline; Vasen, Hans; Burn, John; Nakken, Sigve; Hovig, Eivind; Rødland, Einar Andreas; Tharmaratnam, Kukatharmini; De Vos Tot Nederveen Cappel, Wouter H.; Hill, James; Wijnen, Juul; Jenkins, Mark; Green, Kate; Lalloo, Fiona; Sunde, Lone; Mints, Miriam; Bertario, Lucio; Pineda, Marta; Navarro, Matilde; Morak, Monika; Renkonen-Sinisalo, Laura; Frayling, Ian M.; Plazzer, John-Paul; Pylvanainen, Kirsi; Genuardi, Maurizio; Mecklin, Jukka-Pekka; Möslein, Gabriela; Sampson, Julian R.; Capella, Gabriel (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Objective: Today most patients with Lynch syndrome (LS) survive their first cancer. There is limited information on the incidences and outcome of subsequent cancers. The present study addresses three questions: (i) what ...
Evolution of the cAMP-dependent protein kinase (PKA) catalytic subunit isoforms. 
Søberg, Kristoffer; Moen, Line Victoria; Skålhegg, Bjørn Steen; Lærdahl, Jon Kristen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
The 3’,5’-cyclic adenosine monophosphate (cAMP)-dependent protein kinase, or protein kinase A (PKA), pathway is one of the most versatile and best studied signaling pathways in eukaryotic cells. The two paralogous PKA ...
A Lens for Evaluating Genetic Information Governance Models: Balancing Equity, Efficiency and Sustainability 
Skorve, Espen; Vassilakopoulou, Polyxeni; Aanestad, Margunn; Grunfeld, Thomas Berthold (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
This paper draws from the literature on collective action and the governance of the commons to address the governance of genetic data on variants of specific genes. Specifically, the data arrangements under study relate ...
Characteristics of Blood Vessels in Female Genital Schistosomiasis: Paving the Way for Objective Diagnostics at the Point of Care 
Holmen, Sigve; Galappaththi-Arachchige, Hashini Nilushika; Kleppa, Elisabeth; Pillay, Pavitra; Naicker, Thajasvarie; Taylor, Myra; Onsrud, Mathias; Kjetland, Eyrun Floerecke; Albregtsen, Fritz (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background The mucosal changes associated with female genital schistosomiasis (FGS) encompass abnormal blood vessels. These have been described as circular, reticular, branched, convoluted and having uneven calibre. ...
Aiding genetic analysts: Design of a literature evaluation system 
Børsting, Jorun; Culén, Alma Leora; Eike, Morten Christoph (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
This paper is concerned with the design of a system that handles published research literature evaluation related to clinical DNA sequencing and analysis of genetic variants. The literature handling system is part of a ...
The Opportunity of Linked Data for the European Higher Education Area 
Vega-Gorgojo, Guillermo; Tiropanis, Thanassis; Millard, David (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
The european higher education area (EHEA) aims to create a more comparable, compatible and coherent space of Higher Education in Europe. After a decade of reforms, most of the required instruments are already in place, so ...
Spatial dispersion of elastic waves in a bar characterized by tempered nonlocal elasticity 
Pandey, Vikash; Näsholm, Sven Peter; Sverre, Holm (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)
We apply the framework of tempered fractional calculus to investigate the spatial dispersion of elastic waves in a one-dimensional elastic bar characterized by range-dependent nonlocal interactions. The measure of the ...
Is aging the new disease? 
Woll, Anita (Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2016)
In this paper, we discuss the phenomenon of aging in relation to Hofmann’s three perspectives on disease including disease, illness and sickness role. We further discuss how the introduction of technology supported elderly ...
VSEARCH: a versatile open source tool for metagenomics 
Rognes, Torbjørn; Flouri, Tomáš; Nichols, Ben; Quince, Christopher; Mahé, Frédéric (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background. VSEARCH is an open source and free of charge multithreaded 64-bit tool for processing and preparing metagenomics, genomics and population genomics nucleotide sequence data. It is designed as an alternative to ...
Linking the fractional derivative and the Lomnitz creep law to non-Newtonian time-varying viscosity 
Pandey, Vikash; Holm, Sverre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Many of the most interesting complex media are non-Newtonian and exhibit time-dependent behavior of thixotropy and rheopecty. They may also have temporal responses described by power laws. The material behavior is represented ...
An Ultrasound Robotic System Using the Commercial Robot UR5 
Mathiassen, Kim; Fjellin, Jørgen Enger; Glette, Kyrre Harald; Hol, Per Kristian; Elle, Ole Jakob (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
The use of robots in health care has increased dramatically over the last decade. One area of research has been to use robots to conduct ultrasound examinations, either controlled by a physician or autonomously. This paper ...
Designing for Sustainability: Challenges and Theoretical Considerations 
Srivastava, Swati; Pandey, Sumit (Chapter / Bokkapittel / AcceptedVersion; Peer reviewed, 2016)
Product demand and high consumption have been traditionally viewed as traits of successful business in the mass market. However, the environment is under immense strain to sustain hyper-consumption driven lifestyles fuelled ...
Search, read and write: An inquiry into Web accessibility for dyslexics 
Berget, Gerd; Herstad, Jo; Sandnes, Frode Eika (Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2016)
Universal design in context of digitalisation has become an integrated part of international conventions and national legislations. A goal is to make the Web accessible for people of different genders, ages, backgrounds, ...
When Designers are Non-designers: Open Endedness vs. Structure of Design Tools 
Culén, Alma Leora; Gasparini, Andrea A.; Minaříková, Pavla; Novotný, Roman; Pandey, Sumit; Zbiejczuk Suchá, Ladislava (Chapter / Bokkapittel / AcceptedVersion; Peer reviewed, 2016)
In this paper, we explore types of toolsets that are suitable for design thinking processes, when design teams consist of non-designers. We have conducted a series of workshops to experiment with open-ended, semi-structured ...
Eco-A: Children's Engagement in Environmental and Climate Issues 
Culén, Alma Leora; Eilertsen, Ingeborg; Lægreid, Lone; Pandey, Sumit; Søyland, Magnus; Smørgrav Viddal, Ingrid (Chapter / Bokkapittel / AcceptedVersion; Peer reviewed, 2016)
The paper describes experiences with Eco-A, an interactive installation for children and youth. The installation was designed to engage children and youth in active conversation around environmental and climate issues. It ...
A Robot Avatar: Easier Access to Education and Reduction in Isolation? 
Børsting, Jorun; Culén, Alma Leora (Chapter / Bokkapittel / AcceptedVersion; Peer reviewed, 2016)
This paper presents a qualitative study of deployment and use of a robot as a sick child’s avatar at school. Many children and youth suffer from a range of chronic illnesses that make them, often for long stretches of time, ...
Profiling networks of distinct immune-cells in tumors 
Clancy, Trevor; Hovig, Eivind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background It is now clearly evident that cancer outcome and response to therapy is guided by diverse immune-cell activity in tumors. Presently, a key challenge is to comprehensively identify networks of ...
eRegistries: Electronic registries for maternal and child health 
Frøen, Frederik; Myhre, Sonja; Frost, Michael James; Chou, Doris; Mehl, Garrett; Say, Lale; Cheng, Socheat; Fjeldheim, Ingvild; Friberg, Ingrid; French, Steve; Jani-Bølstad, Jagrati; Kaye, Jane; Lewis, John; Lunde, Ane Kathrine; Mørkrid, Kjersti; Nankabirwa, Victoria; Nyanchoka, Linda; Stone, Hollie; Venkateswaran, Mahima; Wojcieszek, Aleena M; Temmerman, Marleen; Flenady, Vicki J (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background The Global Roadmap for Health Measurement and Accountability sees integrated systems for health information as key to obtaining seamless, sustainable, and secure information exchanges at all levels of health ...
Teamwork Quality and Project Success in Software Development: A Survey of Agile Development Teams 
Lindsjørn, Yngve; Sjøberg, Dag; Dingsøyr, Torgeir; Bergersen, Gunnar R.; Dybå, Tore (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Small, self-directed teams are central in agile development. This article investigates the effect of team- work quality on team performance, learning and work satisfaction in agile software teams, and whether this effect ...
eRegistries: governance for electronic maternal and child health registries 
Myhre, Sonja L; Kaye, Jane; Bygrave, Lee A; Aanestad, Margunn; Ghanem, Buthaina; Mechael, Patricia; Frøen, J. F (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background The limited availability of maternal and child health data has limited progress in reducing mortality and morbidity among pregnant women and children. Global health agencies, leaders, and funders ...
OpenSubtitles2016: Extracting Large Parallel Corpora from Movie and TV Subtitles 
Lison, Pierre; Tiedemann, Jörg (Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2016)
We present a new major release of the OpenSubtitles collection of parallel corpora. The release is compiled from a large database of movie and TV subtitles and includes a total of 1689 bitexts spanning 2.6 billion sentences ...
Young and Creative - a Designerly Approach to Enhance Interventions in the Public Space 
Gasparini, Andrea A. (Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2016)
The public space is often offset for young people, where bold and complex routines usually may result in more or less functional solutions, sometimes even in unpleasant design. More than ever the future depends on the ...
A New Fully Differential Adaptive CMOS Line Driver Using Fuzzy Controller Suitable for ADSL Modems 
Dadashi, Ali; Mirmotahari, Omid; Berg, Yngvar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
In this paper, a new principle for an adaptive line driver using Fuzzy logic is presented. This type of line driver can adapt its output impedance and gain, automatically to the applied load using a fuzzy logic controller ...
Redefining part-of-speech classes with distributional semantic models 
Kutuzov, Andrei; Velldal, Erik; Øvrelid, Lilja (Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2016)
This paper studies how word embeddings trained on the British National Corpus interact with part of speech boundaries. Our work targets the Universal PoS tag set, which is currently actively being used for annotation of a ...
HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels 
Holland, Petter; Knævelsrud, Helene; Søreng, Kristiane; Mathai, Benan John; Lystad, Alf Håkon; Pankiv, Serhiy; Bjørndal, Gunnveig Toft; Schultz, Sebastian; Lobert, Viola; Chan, Robin B; Zhou, Bowen; Liestøl, Knut; Carlsson, Sven R; Melia, Thomas J; Di Paolo, Gilbert; Simonsen, Anne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
A fundamental question is how autophagosome formation is regulated. Here we show that the PX domain protein HS1BP3 is a negative regulator of autophagosome formation. HS1BP3 depletion increased the formation of LC3-positive ...
Memetic Robot Control Evolution and Adaption to Reality 
Ruud, Else-Line Malene; Samuelsen, Eivind; Glette, Kyrre (Chapter / Bokkapittel / AcceptedVersion; Peer reviewed, 2016)
Inspired by animals’ ability to learn and adapt to changes in their environment during life, hybrid evolutionary algorithms have been developed and successfully applied in a number of research areas. This paper explores ...
Evolutionary redesign of the Atlantic cod (Gadus morhua L.) Toll-like receptor repertoire by gene losses and expansions 
Solbakken, Monica Hongrø; Tørresen, Ole Kristian; Nederbragt, Alexander Johan; Seppola, Marit; Gregers, Tone Fredsvik; Jakobsen, Kjetill Sigurd; Jentoft, Sissel (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Genome sequencing of the teleost Atlantic cod demonstrated loss of the Major Histocompatibility Complex (MHC) class II, an extreme gene expansion of MHC class I and gene expansions and losses in the innate pattern recognition ...
Designing for Prolonged Mastery. On involving old people in Participatory Design 
Joshi, Suhas Govind; Bratteteig, Tone (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
In this paper, we report on a participatory design (PD) process with old users. We discuss how we organized and carried out the process so that our users could participate in the mutual learning and co-construction activities ...
Designing for Capacities Rather Than Disabilities. Investigating the relationship between psychomotor capacities and interaction opportunities 
Joshi, Suhas Govind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
This paper explores how designing based on psychomotor capacities instead of disabilities can reconnect old people with technology. We introduce four alternative designs for radios to demonstrate how facilitating a design ...
Proto Design Practice: translating design thinking practices to organizational settings 
Pandey, Sumit (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
The nature of services is becoming complex, indeterminate and often transformational and hence designed solutions need to allow for continuous and ongoing evolution by building up organizational capacity for sustained ...
The Land of Confusion – Clearing up some common misunderstandings of interpretive research 
Munkvold, Bjørn Erik; Bygstad, Bendik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Qualitative research approaches are now well established in information systems research, and are given equal weight as quantitative research in research methods courses in graduate programs. Similar, the heated paradigm ...
PepeSearch: Semantic Data for the Masses 
Vega-Gorgojo, Guillermo; Giese, Martin; Heggestøyl, Simen; Soylu, Ahmet; Waaler, Arild (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
With the emergence of the Web of Data, there is a need of tools for searching and exploring the growing amount of semantic data. Unfortunately, such tools are scarce and typically require knowledge of SPARQL/RDF. We propose ...
Reflections on Behavioural Computer Science 
Johansen, Christian; Pedersen, Tore; Jøsang, Audun (Research report / Forskningsrapport / PublishedVersionAcceptedVersionPublishedVersionAcceptedVersion; Peer reviewed, 2016)
The rapidly increasing pervasiveness and integration of computers in human and animal society calls for a broad discipline under which this development can be studied. We argue that to design and use technology one needs ...
A qualitative study of success criteria in Norwegian agile software projects from suppliers’ perspective 
Siddique, Lubna; Hussein, Bassam A. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
This paper provides practical insights into the success criteria in agile projects in the Norwegian software industry. We conducted 32 interviews with practitioners working with agile projects. The findings revealed two ...
Efficient network isolation and load balancing in multi-tenant HPC clusters 
Zahid, Feroz; Gran, Ernst Gunnar; Bogdanski, Bartosz; Johnsen, Bjørn Dag; Skeie, Tor (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)
Multi-tenancy promises high utilization of available system resources and helps maintaining costeffective operations for service providers. However, multi-tenant high-performance computing (HPC) infrastructures, like dynamic ...
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice 
Skarpengland, Tonje; Holm, Sverre; Scheffler, Katja; Gregersen, Ida; Dahl, Tuva Børresdatter; Suganthan, Rajikala; Segers, Filip; Østlie, Ingunn; Otten, Jeroen J.T.; Gomez, Luisa Fernanda Luna; Ketelhuth, Daniel F.J.; Lundberg, Anna M.; Neurauter, Christine Gran; Hildrestrand, Gunn Annette; Skjelland, Mona; Bjørndal, Bodil; Svardal, Asbjørn M.; Iversen, Per Ole; Hedin, Ulf; Nygård, Ståle; Olstad, Ole Kristoffer; Krohg-Sørensen, Kirsten; Slupphaug, Geir; Eide, Lars; Kusnierczyk, Anna; Folkersen, Lasse; Ueland, Thor; Berge, Rolf Kristian; Hansson, Göran K.; Biessen, Erik A.L.; Halvorsen, Bente; Bjørås, Magnar; Aukrust, Pål (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Increasing evidence suggests that oxidative DNA damage accumulates in atherosclerosis. Recently, we showed that a genetic variant in the human DNA repair enzyme NEIL3 was associated with increased risk of myocardial ...
Grounded Theory Study of Conflicts in Norwegian Agile Software Projects: The Project Managers’ Perspective 
Siddique, Lubna; Hussein, Bassam A. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
This paper aims to explore the process of conflicts in agile software projects. The purpose was to investigate the causes and consequences of these conflicts. For this purpose, we conducted a qualitative study involving ...
Local favoritism in at-large proportional representation systems 
Fiva, Jon H.; Halse, Askill Harkjerr (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)
Pork barrel spending is typically attributed to the strategic behavior of political elites hoping to be electorally rewarded by voters residing in their districts. Such behavior is expected to depend on the incentives ...
How to say that you're special: Can we use bits in the IPv4 header? 
Barik, Runa; Welzl, Michael; Elmokashfi, Ahmed (Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2016)
The IP header should be the ideal part of a packet that an end sys- tem could use to ask the network for special treatment. Recently, there has been renewed interest in using bits of this header – e.g. the ECN and the ...
The Mycobacterium tuberculosis transcriptional landscape under genotoxic stress 
Namouchi, Amine; Gomez Munoz, Marta; Frye, Stephan Alfons; Moen, Line Victoria; Rognes, Torbjørn; Tonjum, Tone; Balasingham, Seetha (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background: As an intracellular human pathogen, Mycobacterium tuberculosis (Mtb) is facing multiple stressful stimuli inside the macrophage and the granuloma. Understanding Mtb responses to stress is essential to identify ...
cnvScan: a CNV screening and annotation tool to improve the clinical utility of computational CNV prediction from exome sequencing data 
Samarakoon, Pubudu S; Sorte, Hanne S; Stray-Pedersen, Asbjørg; Rødningen, Olaug K; Rognes, Torbjørn; Lyle, Robert (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background With advances in next generation sequencing technology and analysis methods, single nucleotide variants (SNVs) and indels can be detected with high sensitivity and specificity in exome sequencing ...
Start Me Up: Determining and Sharing TCP's Initial Congestion Window 
Islam, Safiqul; Welzl, Michael (Chapter / Bokkapittel / AcceptedVersion; Peer reviewed, 2016)
When multiple TCP connections are used between the same host pair, they often share a common bottleneck – especially when they are encapsulated together, e.g. in VPN scenarios. Then, all connections after the first should ...
Open-Source Sequence Clustering Methods Improve the State Of the Art 
Kopylova, Evguenia; Navas-Molina, Jose A.; Mercier, Céline; Xu, Zhenjiang Zech; Mahé, Frédéric; He, Yan; Zhou, Hong-Wei; Rognes, Torbjørn; Caporaso, J. Gregory; Knight, Rob (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Sequence clustering is a common early step in amplicon-based microbial community analysis, when raw sequencing reads are clustered into operational taxonomic units (OTUs) to reduce the run time of subsequent analysis steps. ...
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