Background Policymakers need regular high-quality coverage data on care around the time of birth to accelerate progress for ending preventable maternal and newborn deaths and stillbirths. With increasing ...

Electroencephalography (EEG) and magnetoencephalography (MEG) are among the most important techniques for non-invasively studying cognition and disease in the human brain. These signals are known to originate from cortical ...

Background Studies of shifts in microbial community composition has many applications. For studies at species or subspecies levels, the 16S amplicon sequencing lacks resolution and is often replaced by ...

Background This trial evaluates interventions that utilize data entered at point-of-care in the Palestinian maternal and child eRegistry to generate Quality Improvement Dashboards (QID) for healthcare ...

Colonoscopy is considered the gold standard for detection of colorectal cancer and its precursors. Existing examination methods are, however, hampered by high overall miss-rate, and many abnormalities are left undetected. ...

Background With a motivation of quality assurance, machine learning techniques were trained to classify Norwegian radiology reports of paediatric CT examinations according to their description of abnormal ...

Background Machine learning involves strategies and algorithms that may assist bioinformatics analyses in terms of data mining and knowledge discovery. In several applications, viz. in Life Sciences, it is ...

Algorithmic decision-making is rapidly evolving as a source of data-driven competitive advantage with important implications for analytical practices in multiple settings. Despite the ambitions for algorithmic and intelligent ...

Abstract When recording neural activity from extracellular electrodes, both in vivo and in vitro , spike sorting is a required and very important processing step that allows for identification of single neurons’ activity. ...

Background Advances in whole genome sequencing strategies have provided the opportunity for genomic and comparative genomic analysis of a vast variety of organisms. The analysis results are highly dependent on the quality ...

In this paper, we study the energy consumption of Narrowband IoT devices. The paper suggests that key to saving energy for NB-IoT devices is the usage of full Discontinuous Reception (DRX), including the use of connected-mode ...

Background There is a need for validated clinical risk scores to identify patients at risk of severe disease and to guide decision-making during the covid-19 pandemic. The National Early Warning Score 2 (NEWS2) is widely ...

Surface electromyography (sEMG) provides an intuitive and non-invasive interface from which to control machines. However, preserving the myoelectric control system’s performance over multiple days is challenging, due to ...

Sixty years have passed since neurosurgeon Nils Lundberg presented his thesis about intracranial pressure (ICP) monitoring, which represents a milestone for its clinical introduction. Monitoring of ICP has since become a ...

Dynamic resource provisioning is an important driver for pay-on-demand cloud computing. Virtualized resources open for resource awareness, such that applications may use resource management strategies to modify their ...

Background Targeted client communication (TCC) using text messages can inform, motivate and remind pregnant and postpartum women of timely utilization of care. The mixed results of the effectiveness of TCC interventions ...

Internet of Things (IoT) is a new technology that is driving the connection of billions of devices around the world. Because these devices are often resource‐constrained and very heterogeneous, this presents unique challenges. ...

Background Graph-based reference genomes have become popular as they allow read mapping and follow-up analyses in settings where the exact haplotypes underlying a high-throughput sequencing experiment are ...

Wireless Sensor Networks (WSNs) typically include thousands of resource-constrained sensors to monitor their surroundings, collect data, and transfer it to remote servers for further processing. Although WSNs are considered ...

THIS STUDY REPORTS ON AN EXPERIMENT THAT tested whether drummers systematically manipulated not only onset but also duration and/or intensity of strokes in order to achieve different timing styles. Twenty-two professional ...

Background The dementia subtype idiopathic normal pressure hydrocephalus (iNPH) has unknown etiology, but one characteristic is elevated intracranial pressure (ICP) wave amplitudes in those individuals who respond with ...

Background The human microbiota contributes to health and well-being. Antimicrobials (AM) have an immediate effect on microbial diversity and composition in the gut, but next to nothing is known about their long-term ...

The aim of this study was the analysis of the risk associated with direct oral anticoagulants (DOACs) in patients undergoing non-elective operations on the proximal aorta due to aortic disease.Methods and resultsData from ...

The study focuses on fragmented information awareness as a result of the cross-use of Digital Learning Environments (DLEs), rather than focusing on the use of individual Learning Management Systems (LMSs). This study goes ...

The cholesterol-sensing nuclear receptor liver X receptor (LXR) and the glucose-sensing transcription factor carbohydrate responsive element-binding protein (ChREBP) are central players in regulating glucose and lipid ...

Table annotation is a key task to improve querying the Web and support the Knowledge Graph population from legacy sources (tables). Last year, the SemTab challenge was introduced to unify different efforts to evaluate table ...

Given the relevance of coordination in the field of global software engineering, this work was carried out to further understand coordination mechanisms. Specifically, we investigated meetings and the collaboration tool ...

Chatbots represent new opportunities for low-threshold preventive mental health support to youths. To provide needed knowledge regarding how to design chatbots for this purpose, we present an exploratory design study where ...

We argue that there is a link between implicit computational complexity theory and the theory of reversible computation. We show that the complexity classes ETIME and P can be captured by inherently reversible programming ...

Autoantibodies to transglutaminase 2 (TG2) are hallmarks of celiac disease. To address B cell tolerance and autoantibody formation to TG2, we generated immunoglobulin knock-in (Ig KI) mice that express a prototypical celiac ...

Defining a representative locality is an urgent challenge in perturbation-based explanation methods, which influences the fidelity and soundness of explanations. We address this issue by proposing a robust and intuitive ...

Antiangiogenic drugs are potentially a useful supplement to neoadjuvant chemotherapy for a subgroup of patients with human epidermal growth factor receptor 2 (HER2) negative breast cancer, but reliable biomarkers for ...

This paper analyzes work activity in the home, e.g., cleaning, performed by two actors, a human and a robot. Nowadays, there are attempts to automate this activity through the use of robots. However, the activity of cleaning, ...

Background A high intake of linoleic acid (LA), the major dietary polyunsaturated fatty acid (PUFA), has previously been associated with reduced cardiovascular (CV) morbidity and mortality in observational studies. ...

Background: In precision cancer medicine, the challenge is to prioritize DNA driver events, account for resistance markers, and procure sufficient information for treatment that maintains patient safety. The MetAction ...

Spectral Doppler measurements are an important part of the standard echocardiographic examination. These measurements give insight into myocardial motion and blood flow providing clinicians with parameters for diagnostic ...

Somatic copy number alterations are a frequent sign of genome instability in cancer. A precise characterization of the genome architecture would reveal underlying instability mechanisms and provide an instrument for outcome ...

Tabular data to Knowledge Graph matching is the process of assigning semantic tags from knowledge graphs (e.g., Wikidata or DBpedia) to the elements of a table. This task is a challenging problem for various reasons, ...

Uncertainty and the pursuit of new ventures are intricately linked. Digital technologies open up new ways for uncertainty handling in the pursuit of novelty. In this paper, we develop a process model that traces the dynamics ...

Data governance is concerned with leveraging the potential value of data in data infrastructures. In IS research, data governance has developed as a management perspective, implying a narrow view of who makes decisions ...

The quality of a dataset used for evaluating data linking methods, techniques, and tools depends on the availability of a set of mappings, called reference alignment, that is known to be correct. In particular, it is crucial ...

Current practice of assessing mood episodes in affective disorders largely depends on subjective observations combined with semi-structured clinical rating scales. Motor activity is an objective observation of the inner ...

DNA methylation (5mC) and hydroxymethylation (5hmC) are chemical modifications of cytosine bases which play a crucial role in epigenetic gene regulation. However, cost, data complexity and unavailability of comprehensive ...

Spatial resolution is defined as a system's ability to separate targets using some kind of criterion, such as the Rayleigh criterion. However, in practice, lateral resolution is often evaluated by measuring the Full Width ...

Background Improved markers of prognosis are needed to stratify patients with early-stage colorectal cancer to refine selection of adjuvant therapy. The aim of the present study was to develop a biomarker of patient ...

In the last 30 years, the contrast-to-noise ratio (CNR) has been used to estimate the contrast and lesion detectability in ultrasound images. Recent studies have shown that the CNR cannot be used with modern beamformers, ...

Most Internet hosts today support multiple access technologies and network interfaces. Multipath transport protocols, like MPTCP, are being deployed (e.g., in smartphones), allowing transparent simultaneous use of multiple ...

We propose a method for jointly estimating intrinsic calibration and internal clock synchronisation for a pantilt- zoom (PTZ) camera using only data that can be acquired in the field during normal operation. Results show ...

Network APIs are moving towards protocol agility, where applications express their needs but not a static protocol binding, and it is up to the layer below the API to choose a suitable protocol. The IETF Transport Services ...

Ever since the agile manifesto was created in 2001, the research community has devoted attention to autonomous teams. This article first examines publications on autonomous agile teams to illustrate how the research has ...

Abstract Summary B- and T-cell receptor repertoires of the adaptive immune system have become a key target for diagnostics and therapeutics research. Consequently, there is a rapidly growing ...

This paper presents an overview of the ImageCLEF 2020 lab that was organized as part of the Conference and Labs of the Evaluation Forum - CLEF Labs 2020. ImageCLEF is an ongoing evaluation initiative (first run in 2003) ...

Abstract In B lymphocytes, the uracil N-glycosylase (UNG) excises genomic uracils made by activation-induced deaminase (AID), thus underpinning antibody gene diversification and oncogenic chromosomal translocations, ...

Meticulous preoperative planning is an important part of any surgery to achieve high levels of precision and avoid complications. Conventional medical 2D images and their corresponding three-dimensional (3D) reconstructions ...

BAKGRUNN Norske retningslinjer for primærforebygging av hjerte- og karsykdom anbefaler bruk av risikoskårmodellen NORRISK-2, med noen tillegg. Vi ønsket å undersøke om NORRISK-2 kunne predikere hjerte- og karsykdom hos ...

This paper presents the derivation and experimental validation of algorithms for modeling and estimation of soft continuum manipulators using Lie group variational integration. Existing approaches are generally limited to ...

The growth of digital ecosystems such as Google, Apple and Uber has led to radical changes in economic activity, work and consumption. It has also challenged established economic, social and organization theory, which has ...

Artificial intelligence is currently a hot topic in medicine. However, medical data is often sparse and hard to obtain due to legal restrictions and lack of medical personnel for the cumbersome and tedious process to ...

Laparoscopic videos can be affected by different distortions which may impact the performance of surgery and introduce surgical errors. In this work, we propose a framework for automatically detecting and identifying such ...

Current ultrasonic Local Positioning Systems (LPS) based on an infrastructure of beacons can provide centimeter-level accuracy employing the spread spectrum technique, which also adds robustness against noise. However, the ...

Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale1,2,3. Here we report the integrative analysis of 2,658 ...

Many scholars have pointed to Austrian subjectivism as an appropriate framework for understanding and studying entrepreneurship. Yet very few empirical studies in the field of entrepreneurship have applied a subjectivist ...

Multi-function swarms are swarms that solve multiple tasks at once. For example, a quadcopter swarm could be tasked with exploring an area of interest while simultaneously functioning as ad-hoc relays. With this type of ...

We used sleep monitoring data from a study that investigated the prevalence, characteristics, risk factors and type of sleep apnea (SA) in 579 patients with paroxysmal atrial fibrillation. Most patients were screened for ...

The object sizes in images are diverse, therefore, capturing multiple scale context information is essential for semantic segmentation. Existing context aggregation methods such as pyramid pooling module (PPM) and atrous ...

Human phosphoglucomutase 1 (PGM1) is an evolutionary conserved enzyme that belongs to the ubiquitous and ancient α-d-phosphohexomutases, a large enzyme superfamily with members in all three domains of life. PGM1 catalyzes ...

Program evolution may reveal bad design decisions, misunderstandings, erroneous code, or erroneous specifications, because problems made early in the design of a system may not be discovered until much later in the life-time ...

Abstract Measurements of the left ventricular (LV) pressure trace are rarely performed despite high clinical interest. We estimated the LV pressure trace for an individual heart by scaling the isovolumic, ejection and ...

How do configurations of humans and algorithms evolve as firms adopt artificial intelligence (AI) capabilities, and what are the implications for work and organization? We explored these questions through a two-year long ...

Narrowband Internet of Things (NB-IoT) is gaining momentum as a promising technology for massive machine type communication. Given that its deployment is rapidly progressing worldwide, measurement campaigns and performance ...

As experimental neuroscience is moving toward more integrative approaches, with a variety of acquisition techniques covering multiple spatiotemporal scales, data management is becoming increasingly challenging for neuroscience ...

Loosely-coupled distributed systems organized as collections of so-called cloud-native microservices are able to adapt to traffic in very fine-grained and flexible ways. For this purpose, the cloud-native microservices ...

Data exchange heavily relies on the notion of incomplete database instances. Several semantics for such instances have been proposed and include open (OWA), closed (CWA), and open-closed (OCWA) world. For all these semantics ...

Testicular germ cell tumours (TGCTs) appear as different histological subtypes or mixtures of these. They show similar, multiple DNA copy number changes, where gain of 12p is pathognomonic. However, few high-resolution ...

In March 2020 the number of confirmed COVID-19 cases in Norway increased rapidly, and the efforts to trace contacts of positive cases were under severe pressure. Contact tracing in Norway is the responsibility of the ...

Experimental studies in neuroscience are producing data at a rapidly increasing rate, providing exciting opportunities and formidable challenges to existing theoretical and modeling approaches. To turn massive datasets ...

Abstract Agile transformation implies that organizations apply agile methods also outside of software development units. One particular way of doing such transformations is to create cross-functional software development ...

Automatic human activity detection, mainly transport-wise, is very relevant for architects and urban planners (among many others) when designing cities, roads, public transportation systems, etc. Such detection allows to ...

A typical approach to reduce speckle in coherent imaging systems, is to average same-target images with different speckle realizations. We study settings where such realizations come from applying different transducer-array ...

Purpose This study aims to evaluate the accuracy of point-based registration (PBR) when used for augmented reality (AR) in laparoscopic liver resection surgery. Material and methods The study was conducted in three ...

To make optimal use of previous experiences, important neural activity sequences must be prioritized during hippocampal replay. Integrating insights about the interplay between CA3 and CA2, we propose a conceptual framework ...

Multipath transport protocols utilize multiple network paths (e.g., WiFi and cellular) to achieve improved performance and reliability, compared with their single-path counterparts. The scheduler of a multipath transport ...

The high heterogeneity of 5G use cases requires the extension of the traditional per-component testing procedures provided by certification organizations, in order to devise and incorporate methodologies that cover the ...

Structural Operational Semantics (SOS) provides a general format to describe a model as a transition system with very powerful synchronization mechanisms. Actor systems are distributed, asynchronously communicating units ...

Abstract We show how the display-map category of finite (symmetric) simplicial complexes can be seen as representing the totality of database schemas and instances in a single mathematical structure. We give a ...

This paper presents a method for testing whether objects in actor languages and active object languages exhibit locally deterministic behavior. We investigate such a method for a class of guarded command programs, abstracting ...

Data in engineering industries is highly standardized and information-dense, and usually distributed across many different sources with incompatible formats and implicit semantics. As such, it provides an ideal use case ...

Large ontologies still pose serious challenges to state-of-the-art ontology alignment systems. In this paper we present an approach that combines a neural embedding model and logic-based modules to accurately divide an ...

Statistical texture analysis of cancer cell nuclei stained for DNA has recently been used to develop a pan-cancer prognostic marker of chromatin heterogeneity. In this study, we instead analysed chromatin organisation by ...

Equality is a fundamental concept in first-order reasoning, yet for connection based proof methods a notoriously challenging one to handle efficiently. While paramodulation is a popular technique for dealing with equality ...

Symbolic execution is an important technique for software analysis, which enables systematic model exploration by following all possible execution paths for a given program. For multithreaded shared variable programs, this ...

This paper investigates Universal Design (UD) through the idea of designing for situated abilities, rather than focusing on designing for disabled users. This shift in perspective from disabilities to abilities is explored ...

Conventional surgical navigation systems rely on preoperative imaging to provide guidance. In laparoscopic liver surgery, insufflation of the abdomen (pneumoperitoneum) can cause deformations on the liver, introducing ...

Introduction: In liver surgery, medical images from pre-operative computed tomography and magnetic resonance imaging are the basis for the decision-making process. These images are used in surgery planning and guidance, ...

Previous studies have shown that miniaturised accelerometers can be used to monitor cardiac function and automatically detect ischemic events. However, accelerometers cannot differentiate between acceleration due to motion ...

In the oil and gas industry, during exploration prospect assessment, explorationists rely on ad hoc manual work practices and tools for developing and communicating multiple hypothetical geological scenarios of the prospect. ...

Background We previously reported that in pathogenic mismatch repair (path_MMR) variant carriers, the incidence of colorectal cancer (CRC) was not reduced when colonoscopy was undertaken more frequently ...

While coordination is assumed to contribute to distributed self-managing work team performance, our knowledge about the factors influencing coordination in such team settings is limited. In the present study, we investigate ...

The latest technical and interaction advancements within the virtual reality (VR) field have marked a new era, not only for VR, but also for VR locomotion. In this era, well-established, prevalent VR locomotion techniques ...