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Now showing items 1101-1107 of 1107
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)
Pathogenic bacteria continuously encounter multiple forms of stress in their hostile environments, which leads to DNA damage. With the new insight into biology offered by genome sequences, the elucidation of the gene content ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
We present an overview of selected computational methods for microRNA prediction. It is especially aimed at viral miRNA detection. As the number of microRNAs increases and the range of genomes encoding miRNAs expands, it ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
The publication of a complete genome sequence is usually accompanied by annotations of its genes. In contrast to protein coding genes, genes for ribosomal RNA (rRNA) are often poorly or inconsistently annotated. This makes ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
3-methyladenine DNA glycosylases initiate repair of cytotoxic and promutagenic alkylated bases in DNA. We demonstrate by comparative modelling that Bacillus cereus AlkD belongs to a new, fifth, structural superfamily of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)
Specific guanine-rich sequence motifs in the human genome have considerable potential to form four-stranded structures known as G-quadruplexes or G4 DNA. The enrichment of these motifs in key chromosomal regions has suggested ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2005)
PARALIGN is a rapid and sensitive similarity search tool for the identification of distantly related sequences in both nucleotide and amino acid sequence databases. Two algorithms are implemented, accelerated Smith–Waterman ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)
Background
High-density tiling microarrays are a powerful tool for the characterization of complete genomes. The two major computational challenges associated with custom-made arrays are design and analysis. Firstly, ...