Now showing items 1-6 of 6

  • Skotheim, Rolf I; Thomassen, Gard O; Eken, Marthe; Lind, Guro E; Micci, Francesca; Ribeiro, Franclim R; Cerveira, Nuno; Teixeira, Manuel R; Heim, Sverre; Rognes, Torbjørn; Lothe, Ragnhild A (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)
    Background The ability to detect neoplasia-specific fusion genes is important not only in cancer research, but also increasingly in clinical settings to ensure that correct diagnosis is made and the optimal ...
  • Eilertsen, Ina Andrassy; Sveen, Anita; Strømme, Jonas Meier; Skotheim, Rolf I.; Nesbakken, Arild; Lothe, Ragnhild A (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    KRAS mutation is a well‐known marker for poor response to targeted treatment and patient prognosis in microsatellite stable (MSS) colorectal cancer (CRC). However, variation in clinical outcomes among patients wild‐type ...
  • Hoff, Andreas Midbøe; Kraggerud, Sigrid M.; Alagaratnam, Sharmini; Berg, Kaja Christine Graue; Johannessen, Bjarne; Høland, Maren; Nilsen, Gro; Lingjærde, Ole Christian; Andrews, Peter W.; Lothe, Ragnhild A; Skotheim, Rolf I. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Testicular germ cell tumours (TGCTs) appear as different histological subtypes or mixtures of these. They show similar, multiple DNA copy number changes, where gain of 12p is pathognomonic. However, few high-resolution ...
  • Carm, Kristina Totland; Hoff, Andreas Midbøe; Bakken, Anne Cathrine; Axcrona, Ulrika; Axcrona, Karol; Lothe, Ragnhild A; Skotheim, Rolf I.; Løvf, Marthe (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Prostate cancer is a highly heterogeneous disease and typically multiple distinct cancer foci are present at primary diagnosis. Molecular classification of prostate cancer can potentially aid the precision of diagnosis and ...
  • Eilertsen, Ina Andrassy; Moosavi, Seyed Hossein; Strømme, Jonas Meier; Nesbakken, Arild; Johannessen, Bjarne; Lothe, Ragnhild A; Sveen, Anita (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Gene expression profiling has increasing relevance in the molecular screening of patients with colorectal cancer (CRC). We investigated potential platform-specific effects on transcriptomic subtyping according to established ...
  • Glaire, Mark A; Domingo, Enric; Sveen, Anita; Bruun, Jarle; Nesbakken, Arild; Nicholson, George; Novelli, Marco; Lawson, Kay; Oukrif, Dahmane; Kildal, Wanja; Danielsen, Håvard Emil; Kerr, Rachel; Kerr, David; Tomlinson, Ian; Lothe, Ragnhild A; Church, David N. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background Intratumoural T-cell infiltrate intensity cortes wrelaith clinical outcome in stage II/III colorectal cancer (CRC). We aimed to determine whether this association varies across this heterogeneous group. Me ...