Browsing Institutt for informatikk by Author "Alseth, Ingrun"

Now showing items 1-3 of 3

  • A new family of proteins related to the HEAT-like repeat DNA glycosylases with affinity for branched DNA structures 
    Backe, Paul Hoff; Simm, Roger; Lærdahl, Jon Kristen; Dalhus, Bjørn; Fagerlund, Annette; Økstad, Ole Andreas Løchen; Rognes, Torbjørn; Alseth, Ingrun; Kolstø, Anne-Brit; Bjørås, Magnar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    The recently discovered HEAT-like repeat (HLR) DNA glycosylase superfamily is widely distributed in all domains of life. The present bioinformatics and phylogenetic analysis shows that HLR DNA glycosylase superfamily members ...
  • A new protein superfamily includes two novel 3-methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD 
    Alseth, Ingrun; Rognes, Torbjørn; Lindbäck, Toril; Solberg, Inger; Robertsen, Kristin; Kristiansen, Knut Ivan; Mainieri, Davide; Lillehagen, Lucy; Kolstø, Anne-Brit; Bjørås, Magnar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
    Soil bacteria are heavily exposed to environmental methylating agents such as methylchloride and may have special requirements for repair of alkylation damage on DNA. We have used functional complementation of an Escherichia ...
  • Structural insight into repair of alkylated DNA by a new superfamily of DNA glycosylases comprising HEAT-like repeats 
    Dalhus, Bjørn; Helle, Ina Høydal; Backe, Paul Hoff; Alseth, Ingrun; Rognes, Torbjørn; Bjørås, Magnar; Lærdahl, Jon Kristen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
    3-methyladenine DNA glycosylases initiate repair of cytotoxic and promutagenic alkylated bases in DNA. We demonstrate by comparative modelling that Bacillus cereus AlkD belongs to a new, fifth, structural superfamily of ...