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The nitric oxide synthase protein system in Bacillus cereus : From gene to 3D structure Restricted Access
Lofstad, Marie (Master thesis / Masteroppgave, 2012)
Human Neil DNA glycosylases - Towards structure determination of a NEIL-DNA complex 
Johansen, Anette (Master thesis / Masteroppgave, 2012)
The repair of DNA damage is crucial for the maintenance of genome stability. In base excision repair, lesion-specific DNA glycosylases recognize and cleave a variety of base lesions. The human Nei-like (NEIL) DNA glycosylases ...
Studies of Electron Transport from Flavodoxin Reductase to NrdI in Bacillus cereus 
Skråmo, Silje (Master thesis / Masteroppgave, 2012)
Ribonucleotide reductase (RNR) catalyses the reduction of the four ribonucleotides to their corresponding deoxyribonucleotides needed for synthesis and repair of DNA. RNR is found in the genome of all living organisms, ...
Identification of cancer-specific transcripts by computational analysis of genome-scale expression data at exon resolution Restricted Access
Johannessen, Bjarne (Master thesis / Masteroppgave, 2011)
Fusion genes have key roles in the development and progression of many human cancers. Detection of oncogenic fusion genes is already implemented in routine diagnostics and fusion proteins are targets in molecularly tailored ...
Studies on s2m, a mobile genetic element of viral genomes Restricted Access
Kofstad, Tone (Master thesis / Masteroppgave, 2010)
A highly conserved RNA-motif, called stem-loop-2-motif (s2m), has been identified in the 3' end of the genomes of viruses belonging to different RNA virus families which infect a broad range of animal species. Currently, ...
Analysis by In Vitro Site-Directed Mutagenesis of the PlnE Component of the Two-Peptide Bacteriocin Plantaricin EF 
Ekblad, Bie (Master thesis / Masteroppgave, 2010)
Bacteriocins are ribosomally synthesized antimicrobial peptides (AMPs) and proteins produced by bacteria. The two-peptide (class-IIb) bacteriocins consist of two different peptides and optimal antimicrobial activity requires ...
Understanding the cell surface interactions of enterotoxicenic Escherichia coli Restricted Access
Trygsland, Siri (Master thesis / Masteroppgave, 2010)
Varmelabilt enterotoxin (LT) er den viktigste virulensfaktoren for det bakterielle patogenet enterotoxigent Escherichia coli (ETEC), som er ansvarlig for reisediaré i utviklingsland. LT består av en enzymatisk aktiv ...
Identification of small molecule inhibitors of the transcription factor c-Myb through structure-based drug design and EMSA analysis Restricted Access
Martinez, Marcus Christoffer Rivertz (Master thesis / Masteroppgave, 2009)
Construction of a Heterologous Expression Vector for Plantaricin F, One of the Peptides Constituting the Two-Peptide Bacteriocin Plantaricin EF 
Jørgenrud, Benedicte Marie (Master thesis / Masteroppgave, 2009)
Certain species of lactic acid bacteria produce and secrete bacteriocins, which are ribosomally synthesized antimicrobial peptides. These peptides recognize and kill target cells by rendering their membrane permeable for ...
Are Chemokines Stored for Regulated Secretion in Rodent Endothelial Cells? 
Wilhelmsen, Linn (Master thesis / Masteroppgave, 2008)
Chemokines are small, secreted proteins (5-15 kDa) that mediate leukocyte transmigration and can be secreted from endothelial cells in a constitutive or regulated manner. Regulated secretion shortens the response time to ...
The three dimensional structure of plantaricin J : Determination, by NMR spectroscopy, of the three dimensional structure of the plantaricin J component of the plantaricin J/K two-peptide bacteriocin 
Haugen, Mads Christofer (Master thesis / Masteroppgave, 2008)
The bacteriocin plantaricin J/K consists of the two peptides PlnJ and PlnK, and the two peptides must be present for optimal bacteriocin function. In this study, the three dimensional structure of the PlnJ peptide was ...
The X-ray crystal structure of the anti-tumor antibody P3Q Restricted Access
Eriksson, Agneta Elisabet (Master thesis / Masteroppgave, 2008)
The use of monoclonal antibodies in the search for anti-cancer therapeutics has been a research field of great potential since the hybridoma technology was introduced by Köhler and Milstein in the mid 70s. The use of ...
Destabilitation of Chlamydomonas reinhardtii rbcL transcripts by changes in their 5’UTR 
Leinaas, Marit Nedkvitne (Master thesis / Masteroppgave, 2008)
This study is part of a project where the Chlamydomonas reindhardtii rbcL 5’UTR is analyzed for its effect on transcript stability. Two different mutated rbcL 5’UTRs were fused to GUS reporter genes, and introduced into ...
Aktivering av p53R2 i celler med normal ekspresjon av RNR sammenlignet med i celler med høy ekspresjon av RNR Restricted Access
Lunde, Turid Helen Felli (Master thesis / Masteroppgave, 2008)
Oppgaven går videre med resultater som er funnet ved forskningsgruppen tidligere om aktivering av ribonukleotid reduktase (RNR) subenhet R2 i celler under hypoksi. Det ble funnet at celler som er gjort resistente mot et ...
Mechanisms involved in retrotranslocation of ricin from the endoplasmic reticulum to the cytosol 
Andersen, Elisabeth (Master thesis / Masteroppgave, 2007)
Newly synthesised proteins are therefore subjected to a strict control machinery in the ER lumen where different chaperones facilitate folding during and after translocation. If the folding process is incomplete, misfolded ...
Ahp A-domener i cyanobakteriell peptid syntetase 
Amlie, Kari Elisabeth (Master thesis / Masteroppgave, 2007)
Cyanobakteriestammer fra slektene Anabaena, Microcystis, Planktothrix og Nostoc er vidt utbredt i elver og sjøer over hele jorden. Disse og andre cyanobakterier bruker store multifunksjonelle enzymer, ikke-ribosomale peptid ...
Kovalent konjugering av SUMO til c-Myb's negativt regulatoriske domene : Etablering av en SUMO-sensor 
Kvaløy, Heidi (Master thesis / Masteroppgave, 2007)
Sammendrag Transkripsjonsfaktorer har en viktig rolle i normale cellefunksjoner, men har også vist seg å være involvert i kreftutvikling. Transkripsjonsfaktoren c-Myb spiller en betydelig rolle i hematopoiesen hvor den ...
Molecular Investigation of Inter-Adenylation Domain Consensus Primers to Aid in the Elucidation of Cyanobacterial Non-Ribosomal Peptide Synthetase Gene Clusters 
Sønju, Tom (Master thesis / Masteroppgave, 2007)
Non-ribosomal peptide synthetases (NRPSs) are highly refined natural machines for the biosynthesis of secondary oligopeptides which cannot be synthesised by the ribosomal machinery. Due to the attractive biological potential ...
Heterologous expression in bacterial and mammalian cells of PRNPIP: a protein that interacts with the prion protein PrPC 
Sakalauskaite, Ausra (Master thesis / Masteroppgave, 2006)
Transmissible spongiform encephalopathies (TSEs) are fatal, neurodegenerative diseases in human and animals, caused by prion protein (PrP). The functions of PrP and the basis of these diseases are still under debate. In ...
Profiling of DNA copy number in sarcomas by array comparative genomic hybridisation and identification of candidate cancer genes 
Polania, Ana Heslanyeth Barragan (Master thesis / Masteroppgave, 2006)
Cancer is a disease resulting from an accumulation of acquired genetic mutations. The consequence is an uncontrolled growth of cells and disruption of normal control mechanisms. Complex chromosomal aberrations such as ...
Photochemical internalisation (PCI) of the pro-apoptotic gene TRAIL : a study of the cellular death mechanisms 
Møllergård, Hanne Mali Thesen (Master thesis / Masteroppgave, 2006)
Photochemical internalisation (PCI) is a method for efficient delivery of macromolecules, like genes used in gene therapy, to the cytosol of cells. Most macromolecules enter a cell by endocytosis and are trapped in the ...
Invariant chain and internalization of mature MHC class II from the cell surface 
Landsverk, Ole J. B. (Master thesis / Masteroppgave, 2005)
The major histocompatibility (MHC) class II molecules present peptides to the T cell receptor on CD4+ lymphocytes. The diversity of the epitopes presented depends critically on the processing of the ingested antigens, and ...
Establishment of a test system for multiparameter analysis of intracellular signal pathways by the use of flow cytometry 
Strand, Martin Frank (Master thesis / Masteroppgave, 2005)
G9a, a putative histone methyl-transferase in Drosophila interacts with Tungus, a protein associated with α-Actinin 
Bjørkmo, Mona (Master thesis / Masteroppgave, 2005)
Histone lysine methylation is considered to be a relatively stable modification associated with important functions in epigenetic gene control and for organizing chromatin domains. Genes encoding mammalian homologues of ...
''Elucidation of the expression patterns and funtions of the SET- domain genes ATX3 and ATX5 in Arabidopsis thaliana'' 
Foam, Napoleon (Master thesis / Masteroppgave, 2005)
Covalent modifications of the DNA and histones through acetylation, phosphorylation, methylation, etc are central to gene regulation, recombination, DNA replication and many other processes in the cell. With respect to ...
Regulation of ABCA1 in hepatocytes by the nuclear receptor PXR 
Tapia, German (Master thesis / Masteroppgave, 2005)
Abstract Nuclear receptors that work as heterodimers with RXR control several aspects of lipid metabolism. One such nuclear receptor, pregnane X receptor (PXR) is the molecular target for a wide variety of endogenous and ...
siRNA som verktøy til transient nedregulering av spesifikke gener 
Hussain, Mujtaba (Master thesis / Masteroppgave, 2005)
NUCKS-proteinet ble oppdaget i 1985 av Anne Carine Østvold og hennes medarbeidere ved Biokjemisk Institutt, Universitetet i Oslo. NUCKS genet er klonet og proteinet nøye karakterisert, men dets biologiske funksjon er ...
 
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Masteroppgave (27)
AuthorAmlie, Kari Elisabeth (1)Andersen, Elisabeth (1)Bjørkmo, Mona (1)Ekblad, Bie (1)Eriksson, Agneta Elisabet (1)... View More
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