Browsing Biokjemi by Title
Now showing items 1-20 of 45
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(Master thesis / Masteroppgave, 2007)Cyanobakteriestammer fra slektene Anabaena, Microcystis, Planktothrix og Nostoc er vidt utbredt i elver og sjøer over hele jorden. Disse og andre cyanobakterier bruker store multifunksjonelle enzymer, ikke-ribosomale peptid ...
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Aktivering av p53R2 i celler med normal ekspresjon av RNR sammenlignet med i celler med høy ekspresjon av RNRRestricted Access (Master thesis / Masteroppgave, 2008)Oppgaven går videre med resultater som er funnet ved forskningsgruppen tidligere om aktivering av ribonukleotid reduktase (RNR) subenhet R2 i celler under hypoksi. Det ble funnet at celler som er gjort resistente mot et ...
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Analyse av interaksjonen mellom topeptidbakteriocinet lactococcin G og immunitetsproteinet til lactococcin GRestricted Access (Master thesis / Hovedoppgave, 2007)Kunnskap om de antimikrobielle peptidene, også om hvordan de tilhørende immunitetsproteinene gjenkjenner og nøytraliserer effekten av disse, er viktig da de antimikrobielle peptidene har potensielle bruksområder som ...
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(Master thesis / Masteroppgave, 2010)Bacteriocins are ribosomally synthesized antimicrobial peptides (AMPs) and proteins produced by bacteria. The two-peptide (class-IIb) bacteriocins consist of two different peptides and optimal antimicrobial activity requires ...
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(Master thesis / Masteroppgave, 2008)Chemokines are small, secreted proteins (5-15 kDa) that mediate leukocyte transmigration and can be secreted from endothelial cells in a constitutive or regulated manner. Regulated secretion shortens the response time to ...
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(Master thesis / Hovedoppgave, 2005)Production of DNA damage is the basis of cancer treatments, such as radiotherapy. The limitation of the treatment dose tends to be how well the tumor and normal cell within the body can tolerate the therapy. In order to ...
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(Master thesis / Hovedoppgave, 2004)Chromosome One Amplified Sequence 2 (COAS2) is a member of the cyclophilin family of proteins (Meza Zepeda et al., 2002). It has 84% amino acid homology to H. sapiens cyclophilin A, also known as Peptidylprolyl Isomerase ...
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(Master thesis / Masteroppgave, 2009)Certain species of lactic acid bacteria produce and secrete bacteriocins, which are ribosomally synthesized antimicrobial peptides. These peptides recognize and kill target cells by rendering their membrane permeable for ...
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(Master thesis / Hovedoppgave, 2007)The hematopoietic transcription factor c-Myb has been reported to be involved in diverse and important cellular functions such as differentiation, proliferation and apoptosis. It has also been implicated in tumorigenesis, ...
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(Master thesis / Masteroppgave, 2008)This study is part of a project where the Chlamydomonas reindhardtii rbcL 5’UTR is analyzed for its effect on transcript stability. Two different mutated rbcL 5’UTRs were fused to GUS reporter genes, and introduced into ...
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(Master thesis / Hovedoppgave, 2005)In isolated rat hepatocytes, okadaic acid and cantharidin activate AMP-activated protein kinase (AMPK) by a naringin-sensitive and a naringin-resistant mechanism respectively, probably through inhibition of protein ...
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(Master thesis / Hovedoppgave, 2005)Perfluoro oktansyre (PFOA) er en peroksisomal proliferator som er kjent for å også gi antiinflammatoriske reaksjoner. Virkningsmekanismen for stoffet i levende dyr er lite kjent. For å få en bedre forståelse av PFOAs ...
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(Master thesis / Masteroppgave, 2005)Covalent modifications of the DNA and histones through acetylation, phosphorylation, methylation, etc are central to gene regulation, recombination, DNA replication and many other processes in the cell. With respect to ...
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(Master thesis / Masteroppgave, 2005)
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(Master thesis / Hovedoppgave, 2005)Vekstfaktorer og vekstfaktorreseptorer er med på å regulere vekst av celler via et nettverk av spesifikke intracellulære signalmekanismer. Binding av vekstfaktorer til reseptorer aktiverer reseptorene slik at signalkjeder ...
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(Master thesis / Masteroppgave, 2005)Histone lysine methylation is considered to be a relatively stable modification associated with important functions in epigenetic gene control and for organizing chromatin domains. Genes encoding mammalian homologues of ...
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(Master thesis / Hovedoppgave, 2007)Lactococcin G er et to-peptid bakteriosin produsert av melkesyrebakterien Lactococcus lactis LMG2081. Peptidene dette bakteriosin består av kalles α og β. Genene lagA og lagB som koder for henholdsvis α- og β-peptidene ble ...
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(Master thesis / Masteroppgave, 2006)Transmissible spongiform encephalopathies (TSEs) are fatal, neurodegenerative diseases in human and animals, caused by prion protein (PrP). The functions of PrP and the basis of these diseases are still under debate. In ...
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(Master thesis / Masteroppgave, 2012)The repair of DNA damage is crucial for the maintenance of genome stability. In base excision repair, lesion-specific DNA glycosylases recognize and cleave a variety of base lesions. The human Nei-like (NEIL) DNA glycosylases ...
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Identification of cancer-specific transcripts by computational analysis of genome-scale expression data at exon resolutionRestricted Access (Master thesis / Masteroppgave, 2011)Fusion genes have key roles in the development and progression of many human cancers. Detection of oncogenic fusion genes is already implemented in routine diagnostics and fusion proteins are targets in molecularly tailored ...