Search
Now showing items 1-10 of 30
(Doctoral thesis / Doktoravhandling, 2020)
The three-dimensional (3D) organization of chromatin in the mammalian cell nucleus plays an important role in the regulation of gene expression. In her Ph.D. thesis, Anna Frida Forsberg has investigated the impact of ...
(Doctoral thesis / Doktoravhandling, 2020)
Pharmacogenomic screens for personalized cancer therapy are the focused biomedical application in this thesis. Due to the complex relationships between targeted cancer drugs and high-dimensional genomic predictors, we have ...
(Doctoral thesis / Doktoravhandling, 2020)
Ischemic heart disease and myocardial infarction increase the risk of fatal heart failure via adverse myocardial remodeling. Cardiac cell death during myocardial infarction results in release of pro-inflammatory factors ...
(Doctoral thesis / Doktoravhandling, 2021)
Organ donor shortage is a global problem, and patients die every day waiting for a transplant. In the field of tissue engineering, a major aim is to grow functional organs and tissues in the lab. Often using the patient’s ...
(Doctoral thesis / Doktoravhandling, 2021)
Despite clear health benefits and recommendations, consumption of vegetables in children remains far too low. Although many studies have focused on increasing vegetable intake by children aged up to 5 years, only a few ...
(Doctoral thesis / Doktoravhandling, 2021)
One in eleven women in Norway will be diagnosed with breast cancer by age 75. Organized mammographic screening can detect early stage breast cancer and reduce deaths from this disease. However, screening involves harms, ...
(Doctoral thesis / Doktoravhandling, 2021)
Cutaneous melanoma is the most rapidly growing malignancy in Norway and is becoming an increasing public health concern. While exposure to ultraviolet radiation (UVR) from the sun and solarium is the primary risk factor, ...
(Doctoral thesis / Doktoravhandling, 2020)
Background: About 30% of patients in hospitals are malnourished or at risk of malnutrition. Malnutrition is associated with increased morbidity, longer convalescence, prolonged length of hospital stay, higher readmission ...
(Doctoral thesis / Doktoravhandling, 2020)
T cells are major players in the immune system. These cells can recognize dangerous antigens through their specific receptors. Harnessing the power of T cells would be beneficial for not only fighting numerous infectious ...
(Doctoral thesis / Doktoravhandling, 2020)
Genetically modified mice are important tools in the effort to understand neurodegenerative conditions and identify potential therapeutic targets. A wide range of transgenic mouse models have been developed, but since each ...