Now showing items 1155-1174 of 1318

  • Hem, Cecilie D; Sundvold-Gjerstad, Vibeke; Granum, Stine; Koll, Lise; Abrahamsen, Greger; Buday, Laszlo; Spurkland, Anne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Background The Lck and Src binding adaptor protein TSAd (T cell specific adaptor) regulates actin polymerization in T cells and endothelial cells. The molecular details as to how TSAd regulates this process ...
  • Fagerland, Morten W (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
    Background During the last 30 years, the median sample size of research studies published in high-impact medical journals has increased manyfold, while the use of non-parametric tests has increased at the ...
  • Korsvold, Live; Lie, Hanne Cathrine; Mellblom, Anneli; Ruud, Ellen; Loge, Jon Håvard; Finset, Arnstein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Delivering the bad news of a cancer diagnosis to adolescent and young adult (AYA) patients who display strong emotions is particularly challenging not the least because AYAs are at a vulnerable developmental stage. Due to ...
  • Stahl, Katja; Rahmani, Soulmaz; Prydz, Agnete; Skauli, Nadia; MacAulay, Nanna; Mylonakou, Maria-Niki; Torp, Reidun; Skare, Øivind; Berg, Torill; Leergaard, Trygve Brauns; Paulsen, Ragnhild Elisabeth; Ottersen, Ole Petter; Amiry-Moghaddam, Mahmood (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    More than 90% of the cases of Parkinson's disease have unknown etiology. Gradual loss of dopaminergic neurons of substantia nigra is the main cause of morbidity in this disease. External factors such as environmental toxins ...
  • Rao, Shreyas Balachandra; Katoozi, Shirin; Skauli, Nadia; Froehner, Stanley C.; Ottersen, Ole Petter; Adams, Marvin E.; Amiry-Moghaddam, Mahmood (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Proper function of the retina depends heavily on a specialized form of retinal glia called Müller cells. These cells carry out important homeostatic functions that are contingent on their polarized nature. Specifically, ...
  • Gilmour, Brian Christopher; Gudmundsrud, Ruben; Frank, Johannes; Hov, Amund; Hindkjær Lautrup, Sofie; Aman, Yahyah; Røsjø, Helge; Brenner, Charles; Ziegler, Mathias; Tysnes, Ole-Bjørn; Tzoulis, Charalampos; Omland, Torbjørn; Søraas, Arne Vasli; Holmøy, Trygve; Bergersen, Linda Hildegard; Storm-Mathisen, Jon; Nilsen, Hilde; Fang, Evandro Fei (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
    Nicotinamide adenine dinucleotide (NAD+) plays a fundamental role in life and health through the regulation of energy biogenesis, redox homeostasis, cell metabolism, and the arbitration of cell survival via linkages to ...
  • Joel, Mrinal; Mughal, Awais A; Grieg, Zanina; Murrell, Wayne; Palmero, Sheryl; Mikkelsen, Birthe; Fjerdingstad, Hege B; Sandberg, Cecilie J; Behnan, Jinan; Glover, Joel C; Langmoen, Iver A; Stangeland, Biljana (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Background Glioblastomas are invasive therapy resistant brain tumors with extremely poor prognosis. The Glioma initiating cell (GIC) population contributes to therapeutic resistance and tumor recurrence. ...
  • Herhaus, Lina; Bhaskara, Ramachandra M; Lystad, Alf Håkon; Gestal-Mato, Uxia; Covarrubias-Pinto, Adriana; Bonn, Florian; Simonsen, Anne; Hummer, Gerhard; Dikic, Ivan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Autophagy is a highly conserved catabolic process through which defective or otherwise harmful cellular components are targeted for degradation via the lysosomal route. Regulatory pathways, involving post‐translational ...
  • Azqueta, Amaya; Muruzabal, Damian; Boutet-Robinet, Elisa; Milic, Mirta; Dusinska, Maria; Brunborg, Gunnar; Møller, Peter; Collins, Andrew R. (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    The comet assay (single cell gel electrophoresis) is widely used as a biomonitoring tool to assess DNA damage – strand breaks, as well as oxidised bases; it can also be adapted to measure DNA repair. It is based on the ...
  • Klepp, Knut-Inge; Wind, Marianne; de Bourdeaudhuij, Ilse; Rodrigo, Carmen P; Due, Pernille; Bjelland, Mona; Brug, Johannes (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
    Background Fruit and vegetable intake is low among European children and exposure to TV is negatively associated with the intake of fruit and vegetables. The aim of the present study was to explore exposure ...
  • Winje, Brita A; Røislien, Jo; Frøen, J F (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
    Background Fetal movement counting has long been suggested as a screening tool to identify impaired placental function. However, quantitative limits for decreased fetal movement perform poorly for screening ...
  • Manueldas, Sophia; Benterud, Torkil; Rueegg, Corina Silvia; Garberg, Håvard Tetlie; Huun, Marianne Ullestad; Pankratov, Leonid; Atneosen-Åsegg, Monica; Solberg, Rønnaug; Escobar, Javier; Saugstad, Ola Didrik; Baumbusch, Lars Oliver (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Heart failure is associated with low cardiac output (CO) and low brain perfusion that imposes a significant risk for accelerated brain ageing and Alzheimer’s disease (AD) development. Although clinical heart failure can ...
  • Aasebø, Ida E. J.; Lepperød, Mikkel Elle; Stavrinou, Maria; Nøkkevangen, Sandra; Einevoll, Gaute; Hafting, Torkel; Fyhn, Marianne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    The activity pattern and temporal dynamics within and between neuron ensembles are essential features of information processing and believed to be profoundly affected by anesthesia. Much of our general understanding of ...
  • Barder, Helene; Sundet, Kjetil Søren; Rund, Bjørn Rishovd; Evensen, Julie Horgen; Haahr, Ulrik; Hegelstad, Wenche; Joa, Inge; Johannessen, Jan Olav; Langeveld, Johannes H.; Larsen, Tor Ketil; Melle, Ingrid; Ilner, Stein E. Opjordsmoen; Røssberg, Jan Ivar; Simonsen, Erik; Vaglum, Per Jørgen Wiggen; McGlashan, Thomas; Friis, Svein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    Objective: Neurocognitive impairment is commonly reported at onset of psychotic disorders. However, the long-term neurocognitive course remains largely uninvestigated in first episode psychosis (FEP) and the relationship ...
  • Tsuruda, Kaitlyn; Hofvind, Solveig; Akslen, Lars A.; Hoff, Solveig Roth; Veierød, Marit Bragelien (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Objectives: Women diagnosed with breast cancer are offered treatment and therapy based on tumor characteristics, including tumor diameter. There is scarce knowledge whether tumor diameter is accurately reported, or whether ...
  • Parr, Christine L; Veierød, Marit B; Laake, Petter; Lund, Eiliv; Hjartåker, Anette (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
    Background The Norwegian Women and Cancer Study (NOWAC) is a national population-based cohort study with 102 443 women enrolled at age 30–70 y from 1991 to 1997. The present study was a methodological ...
  • Aune, Erlend; Røislien, Jo; Mathisen, Mariann; Thelle, Dag S; Erik Otterstad, Jan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background Smokers have been shown to have lower mortality after acute coronary syndrome than non-smokers. This has been attributed to the younger age, lower co-morbidity, more aggressive treatment and lower ...
  • Sagvolden, Terje (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
    Background ADHD is currently defined as a cognitive/behavioral developmental disorder where all clinical criteria are behavioral. Overactivity, impulsiveness, and inattentiveness are presently regarded as ...
  • Jendresen, Charlotte; Årskog, Vibeke; Daws, Michael R; Nilsson, Lars N G (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background Triggering receptor expressed on myeloid cells 2 (TREM2) and apolipoprotein E (APOE) are genetically linked to Alzheimer’s disease. Here, we investigated whether human ApoE mediates signal ...
  • Morseth, Bente; Løchen, Maja-Lisa; Ariansen, Inger Kristine Holtermann; Myrstad, Marius; Thelle, Dag Steinar (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Although commonly associated with cardiovascular disease or other medical conditions, atrial fibrillation may also occur in individuals without any known underlying conditions. This manifestation of atrial fibrillation has ...