Browsing Institutt for medisinske basalfag by Title

Now showing items 1495-1514 of 1961

  • Quality control for Illumina 450K methylation data in the absence of iDat files using correlation structure in pedigrees and repeated measures 
    LeBlanc, Marissa; Nustad, Haakon E; Zucknick, Manuela; Page, Christian M (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background An important feature in many genomic studies is quality control and normalization. This is particularly important when analyzing epigenetic data, where the process of obtaining measurements can ...
  • Quantification of adipose tissues by Dual-Energy X-Ray Absorptiometry and Computed Tomography in colorectal cancer patients 
    Alavi, Dena Helene; Henriksen, Hege; Lauritzen, Peter Mæhre; Kværner, Ane Sørlie; Sakinis, Tomas; Langleite, Torgrim Mikal; Henriksen, Christine; Bøhn, Siv Kjølsrud; Paur, Ingvild; Wiedswang, Gro; Smeland, Sigbjørn; Blomhoff, Rune (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background & aims Excess adipose tissue may affect colorectal cancer (CRC) patients' disease progression and treatment. In contrast to the commonly used anthropometric measurements, Dual-Energy X-Ray Absorptiometry (DXA) ...
  • Quantifying bacterial evolution in the wild: A birthday problem for Campylobacter lineages 
    Calland, Jessica K.; Pascoe, Ben; Bayliss, Sion; Mourkas, Evangelos; Berthenet, Elvire; Thorpe, Harry Arthur Frank Wright; Hitchings, Matthew D.; Feil, Edward J.; Corander, Jukka; Blaser, Martin J.; Falush, Daniel; Sheppard, Samuel K. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Measuring molecular evolution in bacteria typically requires estimation of the rate at which nucleotide changes accumulate in strains sampled at different times that share a common ancestor. This approach has been useful ...
  • Quantifying cellular parameters across the murine brain: New practices for integrating and analysing neuroscience data using 3D brain atlases 
    Bjerke, Ingvild Elise (Doctoral thesis / Doktoravhandling, 2021)
    Efforts to advance our understanding of the brain has led to an exponentially growing number of publications. However, research reporting practices are often insufficient for independent researchers to interpret and replicate ...
  • Quantifying the transmission dynamics of MRSA in the community and healthcare settings in a low-prevalence country 
    Di Ruscio, Francesco; Guzzetta, Giorgio; Bjørnholt, Jørgen; Leegaard, Truls Michael; Moen, Aina Elisabeth Fossum; Merler, Stefano; De Blasio, Birgitte Freiesleben (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Methicillin-resistant Staphylococcus aureus (MRSA) is a primarily nosocomial pathogen that, in recent years, has increasingly spread to the general population. The rising prevalence of MRSA in the community implies more ...
  • Quantitative proteomics reveals protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls 
    Cappelletti, Chiara; Eriksson, Anna; Brorson, Ina S.; Leikfoss, Ingvild S.; Kråbøl, Oda; Høgestøl, Einar A.; Vitelli, Valeria; Mjaavatten, Olav; Harbo, Hanne F.; Berven, Frode; Bos, Steffan D.; Berge, Tone (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background Multiple sclerosis (MS) is an autoimmune, neurodegenerative disorder with a strong genetic component that acts in a complex interaction with environmental factors for disease development. CD4+ ...
  • QUINT: Workflow for Quantification and Spatial Analysis of Features in Histological Images From Rodent Brain 
    Yates, Sharon Christine; Groeneboom, Nicolaas Ervik; Coello, Christopher; Lichtenthaler, Stefan F.; Kuhn, Peer-Hendrik; Demuth, Hans-Ulrich; Hartlage-Rübsamen, Maike; Rossner, Steffen; Leergaard, Trygve B.; Kreshuk, Anna; Puchades, Maja; Bjaalie, Jan G. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Transgenic animal models are invaluable research tools for elucidating the pathways and mechanisms involved in the development of neurodegenerative diseases. Mechanistic clues can be revealed by applying labelling techniques ...
  • Rab7b modulates autophagic flux by interacting with Atg4B 
    Kjos, Ingrid; Distefano, Marita Borg; Sætre, Frank Ove; Repnik, Urska; Holland, Petter; Jones, Arwyn T; Engedal, Nikolai; Simonsen, Anne; Bakke, Oddmund; Progida, Cinzia (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Autophagy (macroautophagy) is a highly conserved eukaryotic degradation pathway in which cytosolic components and organelles are sequestered by specialized autophagic membranes and degraded through the lysosomal system. ...
  • Radiation induces EIF2AK3/PERK and ERN1/IRE1 mediated pro-survival autophagy 
    Chaurasia, Madhuri; Gupta, Swapnil; Das, Asmita; Dwarakanath, B. S.; Simonsen, Anne; Sharma, Kulbhushan (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Cellular effects of ionizing radiation include oxidative damage to macromolecules, unfolded protein response (UPR) and metabolic imbalances. Oxidative stress and UPR have been shown to induce macroautophagy/autophagy in a ...
  • Rapid recovery and altered neurochemical dependence of locomotor central pattern generation following lumbar neonatal spinal cord injury 
    Züchner, Mark; Kondratska, Olena; Sylte, Camilla; Glover, Joel; Boulland, Jean-Luc (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Following incomplete compression injury in the thoracic spinal cord of neonatal mice 1 day after birth (P1), we previously reported that virtually normal hindlimb locomotor function is recovered within about 3 weeks despite ...
  • Rapid, Large, and Synchronous Sweat and Cardiovascular Responses Upon Minor Stimuli in Healthy Subjects. Dynamics and Reproducibility 
    Ho, Ai Van Thuy; Toska, Karin; Wesche, Jarlis (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Purpose: The aim of the study was to investigate steady state levels, dynamics and reproducibility of cardiovascular variables and electrodermal activity in different skin areas in response to minor physiological and mental ...
  • Re-oxygenation after anoxia induces brain cell death and memory loss in the anoxia-tolerant crucian carp 
    Lefevre, Sjannie; Stecyk, Jonathan A. W.; Torp, May-Kristin; Løvold, Lisa Yuen; Sørensen, Christina; Johansen, Ida Beitnes; Stensløkken, Kåre-Olav; Couturier, Christine; Sloman, Katherine A.; Nilsson, Göran Erik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Crucian carp (Carassius carassius) survive without oxygen for several months, but it is unknown whether they are able to protect themselves from cell death normally caused by the absence, and particularly return, of oxygen. ...
  • Real-time imaging of polymersome nanoparticles in zebrafish embryos engrafted with melanoma cancer cells: Localization, toxicity and treatment analysis 
    Kocere, Agnese; Resseguier, Julien; Wohlmann, Jens; Skjeldal, Frode Miltzow; Khan, Shanawaz; Speth, Martin; Dal, Nils-Jørgen Knudsen; Ng, Matthew Yoke Wui; Alonso Rodriguez, Noelia; Scarpa, Edoardo; Rizzello, Loris; Battaglia, Giuseppe; Griffiths, Gareth Wyn; Fenaroli, Federico (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background The developing zebrafish is an emerging tool in nanomedicine, allowing non-invasive live imaging of the whole animal at higher resolution than is possible in the more commonly used mouse models. In addition, ...
  • Realization of the right to adequate food and the nutritional status of land evictees: a case for mothers/caregivers and their children in rural Central Uganda 
    Nahalomo, Aziiza; Iversen, Per O; Rukundo, Peter M; Kaaya, Archileo; Kikafunda, Joyce; Eide, Wenche B; Marais, Maritha; Wamala, Edward; Kabahenda, Margaret (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background In developing countries like Uganda, the human right to adequate food (RtAF) is inextricably linked to access to land for households to feed themselves directly through production or means for ...
  • Recellularization of decellularized venous grafts using peripheral blood: a critical evaluation 
    Rambøl, Mia Marie-Elisabeth; Hisdal, Jonny; Sundhagen, Jon Otto; Brinchmann, Jan E.; Rosales, Antonio (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Vascular disease is a major cause of death worldwide, and the growing need for replacement vessels is not fully met by autologous grafts or synthetic alternatives. Tissue engineering has emerged as a compelling strategy ...
  • Recommendations for the surveillance of cancer-related fatigue in childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group 
    Christen, Salome; Roser, Katharina; Mulder, Renee L.; Ilic, Anica; Lie, Hanne Cathrine; Loonen, Jacqueline J.; Mellblom, Anneli; Kremer, Leontien; Hudson, Melissa M.; Constine, Louis Sandy; Skinner, Roderick; Scheinemann, Katrin; Gilleland Marchak, Jordan; Michel, Gisela (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract Purpose Cancer-related fatigue (CRF) negatively affects the lives of childhood, adolescent, and young adult (CAYA) cancer survivors. We aimed to provide an evidence-based clinical practice guideline (CPG) ...
  • Reconstitution of GABA, Glycine and Glutamate Transporters 
    Danbolt, Niels Christian; López-Corcuera, Beatriz; Zhou, Yun (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract In contrast to water soluble enzymes which can be purified and studied while in solution, studies of solute carrier (transporter) proteins require both that the protein of interest is situated in a phospholipid ...
  • Recovering escherichia coli plasmids in the absence of long-read sequencing data 
    Paganini, Julian A.; Plantinga, Nienke L.; Alonso, Sergio Arredondo; Willems, Rob; Schürch, Anita C. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    The incidence of infections caused by multidrug-resistant E. coli strains has risen in the past years. Antibiotic resistance in E. coli is often mediated by acquisition and maintenance of plasmids. The study of E. coli ...
  • Reduced levels of circulating adhesion molecules in adolescents with early-onset psychosis 
    Wedervang-Resell, Kirsten; Ueland, Thor; Aukrust, Pål; Friis, Svein; Holven, Kirsten Bjørklund; Johannessen, Cecilie Haggag; Lekva, Tove; Lonning, Vera; Smelror, Runar; Szabo, Attila; Andreassen, Ole Andreas; Myhre, Anne Margrethe; Agartz, Ingrid (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    It is suggested that neurodevelopmental abnormalities are involved in the disease mechanisms of psychotic disorders. Although cellular adhesion molecules (CAMs) participate in neurodevelopment, modulate blood–brain barrier ...
  • Reduced MCMV Δm157 viral clearance in the absence of TSAd 
    Moussa, P; Abrahamsen, Greger; Fodil, N; Gopalakrishnan, Ramakrishna Prabhu; Mancini, M; Dissen, Erik; Sæther, Per Christian; Wiltshire, SA; Boivin, GA; Caignard, G; Spurkland, Anne; Vidal, SM (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    The T cell specific adapter protein (TSAd) is expressed in activated T cells and NK cells. While TSAd is beginning to emerge as a critical regulator of Lck and Itk activity in T cells, its role in NK cells has not yet been ...