Now showing items 1495-1514 of 1961

  • LeBlanc, Marissa; Nustad, Haakon E; Zucknick, Manuela; Page, Christian M (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background An important feature in many genomic studies is quality control and normalization. This is particularly important when analyzing epigenetic data, where the process of obtaining measurements can ...
  • Alavi, Dena Helene; Henriksen, Hege; Lauritzen, Peter Mæhre; Kværner, Ane Sørlie; Sakinis, Tomas; Langleite, Torgrim Mikal; Henriksen, Christine; Bøhn, Siv Kjølsrud; Paur, Ingvild; Wiedswang, Gro; Smeland, Sigbjørn; Blomhoff, Rune (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background & aims Excess adipose tissue may affect colorectal cancer (CRC) patients' disease progression and treatment. In contrast to the commonly used anthropometric measurements, Dual-Energy X-Ray Absorptiometry (DXA) ...
  • Calland, Jessica K.; Pascoe, Ben; Bayliss, Sion; Mourkas, Evangelos; Berthenet, Elvire; Thorpe, Harry Arthur Frank Wright; Hitchings, Matthew D.; Feil, Edward J.; Corander, Jukka; Blaser, Martin J.; Falush, Daniel; Sheppard, Samuel K. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Measuring molecular evolution in bacteria typically requires estimation of the rate at which nucleotide changes accumulate in strains sampled at different times that share a common ancestor. This approach has been useful ...
  • Bjerke, Ingvild Elise (Doctoral thesis / Doktoravhandling, 2021)
    Efforts to advance our understanding of the brain has led to an exponentially growing number of publications. However, research reporting practices are often insufficient for independent researchers to interpret and replicate ...
  • Di Ruscio, Francesco; Guzzetta, Giorgio; Bjørnholt, Jørgen; Leegaard, Truls Michael; Moen, Aina Elisabeth Fossum; Merler, Stefano; De Blasio, Birgitte Freiesleben (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Methicillin-resistant Staphylococcus aureus (MRSA) is a primarily nosocomial pathogen that, in recent years, has increasingly spread to the general population. The rising prevalence of MRSA in the community implies more ...
  • Cappelletti, Chiara; Eriksson, Anna; Brorson, Ina S.; Leikfoss, Ingvild S.; Kråbøl, Oda; Høgestøl, Einar A.; Vitelli, Valeria; Mjaavatten, Olav; Harbo, Hanne F.; Berven, Frode; Bos, Steffan D.; Berge, Tone (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background Multiple sclerosis (MS) is an autoimmune, neurodegenerative disorder with a strong genetic component that acts in a complex interaction with environmental factors for disease development. CD4+ ...
  • Yates, Sharon Christine; Groeneboom, Nicolaas Ervik; Coello, Christopher; Lichtenthaler, Stefan F.; Kuhn, Peer-Hendrik; Demuth, Hans-Ulrich; Hartlage-Rübsamen, Maike; Rossner, Steffen; Leergaard, Trygve B.; Kreshuk, Anna; Puchades, Maja; Bjaalie, Jan G. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Transgenic animal models are invaluable research tools for elucidating the pathways and mechanisms involved in the development of neurodegenerative diseases. Mechanistic clues can be revealed by applying labelling techniques ...
  • Kjos, Ingrid; Distefano, Marita Borg; Sætre, Frank Ove; Repnik, Urska; Holland, Petter; Jones, Arwyn T; Engedal, Nikolai; Simonsen, Anne; Bakke, Oddmund; Progida, Cinzia (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Autophagy (macroautophagy) is a highly conserved eukaryotic degradation pathway in which cytosolic components and organelles are sequestered by specialized autophagic membranes and degraded through the lysosomal system. ...
  • Chaurasia, Madhuri; Gupta, Swapnil; Das, Asmita; Dwarakanath, B. S.; Simonsen, Anne; Sharma, Kulbhushan (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Cellular effects of ionizing radiation include oxidative damage to macromolecules, unfolded protein response (UPR) and metabolic imbalances. Oxidative stress and UPR have been shown to induce macroautophagy/autophagy in a ...
  • Züchner, Mark; Kondratska, Olena; Sylte, Camilla; Glover, Joel; Boulland, Jean-Luc (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Following incomplete compression injury in the thoracic spinal cord of neonatal mice 1 day after birth (P1), we previously reported that virtually normal hindlimb locomotor function is recovered within about 3 weeks despite ...
  • Ho, Ai Van Thuy; Toska, Karin; Wesche, Jarlis (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Purpose: The aim of the study was to investigate steady state levels, dynamics and reproducibility of cardiovascular variables and electrodermal activity in different skin areas in response to minor physiological and mental ...
  • Lefevre, Sjannie; Stecyk, Jonathan A. W.; Torp, May-Kristin; Løvold, Lisa Yuen; Sørensen, Christina; Johansen, Ida Beitnes; Stensløkken, Kåre-Olav; Couturier, Christine; Sloman, Katherine A.; Nilsson, Göran Erik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Crucian carp (Carassius carassius) survive without oxygen for several months, but it is unknown whether they are able to protect themselves from cell death normally caused by the absence, and particularly return, of oxygen. ...
  • Kocere, Agnese; Resseguier, Julien; Wohlmann, Jens; Skjeldal, Frode Miltzow; Khan, Shanawaz; Speth, Martin; Dal, Nils-Jørgen Knudsen; Ng, Matthew Yoke Wui; Alonso Rodriguez, Noelia; Scarpa, Edoardo; Rizzello, Loris; Battaglia, Giuseppe; Griffiths, Gareth Wyn; Fenaroli, Federico (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background The developing zebrafish is an emerging tool in nanomedicine, allowing non-invasive live imaging of the whole animal at higher resolution than is possible in the more commonly used mouse models. In addition, ...
  • Nahalomo, Aziiza; Iversen, Per O; Rukundo, Peter M; Kaaya, Archileo; Kikafunda, Joyce; Eide, Wenche B; Marais, Maritha; Wamala, Edward; Kabahenda, Margaret (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background In developing countries like Uganda, the human right to adequate food (RtAF) is inextricably linked to access to land for households to feed themselves directly through production or means for ...
  • Rambøl, Mia Marie-Elisabeth; Hisdal, Jonny; Sundhagen, Jon Otto; Brinchmann, Jan E.; Rosales, Antonio (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Vascular disease is a major cause of death worldwide, and the growing need for replacement vessels is not fully met by autologous grafts or synthetic alternatives. Tissue engineering has emerged as a compelling strategy ...
  • Christen, Salome; Roser, Katharina; Mulder, Renee L.; Ilic, Anica; Lie, Hanne Cathrine; Loonen, Jacqueline J.; Mellblom, Anneli; Kremer, Leontien; Hudson, Melissa M.; Constine, Louis Sandy; Skinner, Roderick; Scheinemann, Katrin; Gilleland Marchak, Jordan; Michel, Gisela (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract Purpose Cancer-related fatigue (CRF) negatively affects the lives of childhood, adolescent, and young adult (CAYA) cancer survivors. We aimed to provide an evidence-based clinical practice guideline (CPG) ...
  • Danbolt, Niels Christian; López-Corcuera, Beatriz; Zhou, Yun (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract In contrast to water soluble enzymes which can be purified and studied while in solution, studies of solute carrier (transporter) proteins require both that the protein of interest is situated in a phospholipid ...
  • Paganini, Julian A.; Plantinga, Nienke L.; Alonso, Sergio Arredondo; Willems, Rob; Schürch, Anita C. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    The incidence of infections caused by multidrug-resistant E. coli strains has risen in the past years. Antibiotic resistance in E. coli is often mediated by acquisition and maintenance of plasmids. The study of E. coli ...
  • Wedervang-Resell, Kirsten; Ueland, Thor; Aukrust, Pål; Friis, Svein; Holven, Kirsten Bjørklund; Johannessen, Cecilie Haggag; Lekva, Tove; Lonning, Vera; Smelror, Runar; Szabo, Attila; Andreassen, Ole Andreas; Myhre, Anne Margrethe; Agartz, Ingrid (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    It is suggested that neurodevelopmental abnormalities are involved in the disease mechanisms of psychotic disorders. Although cellular adhesion molecules (CAMs) participate in neurodevelopment, modulate blood–brain barrier ...
  • Moussa, P; Abrahamsen, Greger; Fodil, N; Gopalakrishnan, Ramakrishna Prabhu; Mancini, M; Dissen, Erik; Sæther, Per Christian; Wiltshire, SA; Boivin, GA; Caignard, G; Spurkland, Anne; Vidal, SM (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    The T cell specific adapter protein (TSAd) is expressed in activated T cells and NK cells. While TSAd is beginning to emerge as a critical regulator of Lck and Itk activity in T cells, its role in NK cells has not yet been ...