Browsing Institutt for medisinske basalfag by Title

Now showing items 1272-1291 of 1960

  • Obesity-Susceptibility Loci and Their Influence on Adiposity-Related Traits in Transition from Adolescence to Adulthood - The HUNT Study 
    Cuypers, Koenraad; Loos, Ruth J.F.; Kvaløy, Kirsti; Kulle, Bettina; Romundstad, Pål Richard; Holmen, Turid Lingaas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
    Introduction Obesity-susceptibility loci have been related to adiposity traits in adults and may affect body fat estimates in adolescence. There are indications that different sets of obesity-susceptibility loci influence ...
  • Observed to expected or logistic regression to identify hospitals with high or low 30-day mortality? 
    Kristoffersen, Doris Tove; Helgeland, Jon; Clench-Aas, Jocelyne; Laake, Petter; Veierød, Marit Bragelien (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Introduction: A common quality indicator for monitoring and comparing hospitals is based on death within 30 days of admission. An important use is to determine whether a hospital has higher or lower mortality than other ...
  • Observing Music Therapy in Dementia: Repeated Single-case Studies Assessing Well-being and Sociable Interaction 
    Madsø, Kristine Gustavsen; Molde, Helge; Hynninen, Kia Minna; Nordhus, Inger Hilde Norunn Gjøsæther (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Objectives This study compared behavioral expressions of momentary well-being and sociable behavior toward significant others during music therapy and regular social interaction. Methods A 10-week active music therapy ...
  • Obstructive sleep apnea in community-dwelling adults : A clinical-epidemiological study 
    Hrubos-Strøm, Harald (Doctoral thesis / Doktoravhandling, 2013)
  • Occupational stressors and its organizational and individual correlates: A nationwide study of Norwegian ambulance personnel 
    Sterud, Tom; Hem, Erlend; Ekeberg, Øivind; Lau, Bjørn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)
    Background High levels of stress among ambulance personnel have been attributed to the conditions of ambulance work. However, there is little research to support this notion, and it has been questioned ...
  • Occurrence, chronicity and intensity of itch in a clinical consecutive sample of patients with skin diseases: A multi-centre study in 13 european countries 
    Schut, Christina; Dalgard, Florence; Halvorsen, Jon Anders; Gieler, Uwe; Lien, Lars; Aragones, Lucia Tomas; Poot, Francoise; Jemec, Gregor B.E.; Misery, Laurent; Kemény, Lajos; Sampogna, Francesca; van Middendorp, Henriët; Balieva, Flora Nicol; Linder, Dennis; Szepietöwski, Jacek C.; Lvov, Andrey; Marrón, Servando E.; Altunay, Ilknur K.; Finlay, Andrew Y.; Salek, Sam; Kupfer, Jörg (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Itch is an unpleasant symptom, affecting many dermatological patients. Studies investigating the occurrence and intensity of itch in dermatological patients often focus on a single skin disease and omit a control group ...
  • Ocular findings and ocular graft-versus-host disease after allogeneic stem cell transplantation without total body irradiation 
    Pathak, Meeta; Diep, Phoi Phoi; Lai, Xiaoran; Brinch, Lorentz; Ruud, Ellen; Drolsum, Liv (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Patients treated with allogeneic stem cell transplantation (allo-SCT) often develop ocular complications. To investigate the ocular findings in young long-term survivors after allo-SCT without TBI, we examined 96 patients ...
  • OGT (O-GlcNAC transferase) selectively modifies multiple residues unique to Lamin A 
    Simon, Dan N.; Wriston, Amanda; Fan, Qiong; Shabanowitz, Jeffrey; Florwick, Alyssa; Dharmaraj, Tejas; Peterson, Sherket B.; Gruenbaum, Yosef; Carlson, Cathrine Rein; Grønning-Wang, Line Mariann; Hunt, Donald F.; Wilson, Katherine L. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    The LMNA gene encodes lamins A and C with key roles in nuclear structure, signaling, gene regulation, and genome integrity. Mutations in LMNA cause over 12 diseases (‘laminopathies’). Lamins A and C are identical for their ...
  • Oikopleura 
    Glover, Joel (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
  • On the collapsibility of measures of effect in the counterfactual causal framework 
    Huitfeldt, Anders; Stensrud, Mats J; Suzuki, Etsuji (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    The relationship between collapsibility and confounding has been subject to an extensive and ongoing discussion in the methodological literature. We discuss two subtly different definitions of collapsibility, and show that ...
  • On the Physiology of Experimental Hypoxic-Ischaemic Brain Injury 
    Wood, Thomas (Doctoral thesis / Doktoravhandling, 2017)
  • On the search for an intelligible comet assay descriptor 
    Møller, Peter; Loft, Steffen; Ersson, Clara; Koppen, Gudrun; Dusinska, Maria; Collins, Andrew Richard (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    The comet assay has developed over the past 30 years and today, a variety of different DNA lesions and DNA repair can be measured by different versions of the assay (Collins, 2004). In the final step of the method, an image ...
  • On the use of one-sided statistical tests in biomedical research 
    Murphy, Ricardo (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    There is a tendency to automatically use two-sided tests to assess the statistical significance of experimental results. Yet if a theory predicts the direction of an experimental outcome, or if for some practical (eg ...
  • Oncolytic peptide LTX-315 induces an immune-mediated abscopal effect in a rat sarcoma model 
    Nestvold, Janne M.; Wang, Mengyu; Camilio, Ketil Andre; Zinöcker, Severin; Tjelle, Torunn Elisabeth; Lindberg, Alf; Haug, Bengt Erik; Kvalheim, Gunnar; Sveinbjørnsson, Baldur; Rekdal, Øystein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    LTX 315 is an oncolytic peptide with potent immunological properties. In the present study, we demonstrate that intratumoral treatment with LTX-315 resulted in a complete regression and systemic immune response in a rat ...
  • One year of free school fruit in Norway – 7 years of follow-up 
    Bere, Elling; te Velde, Saskia J; Småstuen, Milada C; Twisk, Jos; Klepp, Knut-Inge (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Background It is important that health-promoting efforts result in sustained behavioural changes, preferably throughout life. However, only a very few intervention studies evaluate long term follow up. ...
  • One-year protocol biopsies from ABO-incompatible renal allografts compared with a matched cohort of ABO-compatible allografts 
    Dörje, Christina; Mjøen, Geir; Strøm, Erik Heyerdahl; Holdaas, Hallvard; Jenssen, Trond Geir; Øyen, Ole; Akkøk, Cigdem Ahaein; Småstuen, Milada C; Midtvedt, Karsten; Reisæter, Anna Varberg (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Introduction Early acute antibody-mediated rejection (ABMR) occurs more frequently in ABO-incompatible (ABOi) than in ABO-compatible (ABOc) kidney transplantation. This could lead to increased inflammation/scarring in ...
  • Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits 
    Toch, Mathilde; Harris, Audrey; Schakman, Olivier; Kondratskaya, Elena; Dauguet, Nicolas; Boulland, Jean-Luc; Debrulle, Stéphanie; Baudouin, Charlotte; Hidalgo-Figueroa, Maria; Mu, Xiuqian; Gow, Alexander; Glover, Joel; Tissir, Fadel; Clotman, Frédéric (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract In the developing spinal cord, Onecut transcription factors control the diversification of motor neurons into distinct neuronal subsets by ensuring the maintenance of Isl1 expression during differentiation. However, ...
  • OPA1-anchored PKA phosphorylates perilipin 1 on S522 and S497 in adipocytes differentiated from human adipose stem cells 
    Rogne, Marie; Chu, Dinh Toi; Küntziger, Thomas M.; Mylonakou, Maria-Niki; Collas, Philippe; Tasken, Kjetil (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Optic atrophy 1 (OPA1) is the A-kinase anchoring protein targeting the pool of protein kinase A (PKA) responsible for perilipin 1 phosphorylation, a gatekeeper for lipolysis. However, the involvement of OPA1-bound PKA in ...
  • Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation 
    Caglayan, Safak; Hashim, Adnan; Cieslar-Pobuda, Artur; Jensen, Vidar; Behringer, Sidney; Talug, Burcu; Chu, Dinh Toi; Pecquet, Christian; Rogne, Marie; Brech, Andreas; Brorson, Sverre Henning; Nagelhus, Erlend Arnulf; Hannibal, Luciana; Boschi, Antonella; Tasken, Kjetil; Staerk, Judith (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Optic atrophy 1 (OPA1), a GTPase at the inner mitochondrial membrane involved in regulating mitochondrial fusion, stability, and energy output, is known to be crucial for neural development: Opa1 heterozygous mice show ...
  • Optogenetic pacing of medial septum parvalbumin-positive cells disrupts temporal but not spatial firing in grid cells 
    Lepperød, Mikkel Elle; Christensen, Ane Charlotte; Lensjø, Kristian Kinden; Buccino, Alessio Paolo; Yu, Jai; Fyhn, Marianne; Hafting, Torkel (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Grid cells in the medial entorhinal cortex (MEC) exhibit remarkable spatial activity patterns with spikes coordinated by theta oscillations driven by the medial septal area (MSA). Spikes from grid cells progress relative ...