Browsing Institutt for medisinske basalfag by Title
Now showing items 1023-1042 of 1575
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Introduction Obesity-susceptibility loci have been related to adiposity traits in adults and may affect body fat estimates in adolescence. There are indications that different sets of obesity-susceptibility loci influence ...
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Observed to expected or logistic regression to identify hospitals with high or low 30-day mortality? (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Introduction: A common quality indicator for monitoring and comparing hospitals is based on death within 30 days of admission. An important use is to determine whether a hospital has higher or lower mortality than other ...
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(Doctoral thesis / Doktoravhandling, 2013)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)Background High levels of stress among ambulance personnel have been attributed to the conditions of ambulance work. However, there is little research to support this notion, and it has been questioned ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Itch is an unpleasant symptom, affecting many dermatological patients. Studies investigating the occurrence and intensity of itch in dermatological patients often focus on a single skin disease and omit a control group ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Patients treated with allogeneic stem cell transplantation (allo-SCT) often develop ocular complications. To investigate the ocular findings in young long-term survivors after allo-SCT without TBI, we examined 96 patients ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)The LMNA gene encodes lamins A and C with key roles in nuclear structure, signaling, gene regulation, and genome integrity. Mutations in LMNA cause over 12 diseases (‘laminopathies’). Lamins A and C are identical for their ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)The relationship between collapsibility and confounding has been subject to an extensive and ongoing discussion in the methodological literature. We discuss two subtly different definitions of collapsibility, and show that ...
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(Doctoral thesis / Doktoravhandling, 2017)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)The comet assay has developed over the past 30 years and today, a variety of different DNA lesions and DNA repair can be measured by different versions of the assay (Collins, 2004). In the final step of the method, an image ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)There is a tendency to automatically use two-sided tests to assess the statistical significance of experimental results. Yet if a theory predicts the direction of an experimental outcome, or if for some practical (eg ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)LTX 315 is an oncolytic peptide with potent immunological properties. In the present study, we demonstrate that intratumoral treatment with LTX-315 resulted in a complete regression and systemic immune response in a rat ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background It is important that health-promoting efforts result in sustained behavioural changes, preferably throughout life. However, only a very few intervention studies evaluate long term follow up. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Abstract In the developing spinal cord, Onecut transcription factors control the diversification of motor neurons into distinct neuronal subsets by ensuring the maintenance of Isl1 expression during differentiation. However, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Optic atrophy 1 (OPA1) is the A-kinase anchoring protein targeting the pool of protein kinase A (PKA) responsible for perilipin 1 phosphorylation, a gatekeeper for lipolysis. However, the involvement of OPA1-bound PKA in ...
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Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Optic atrophy 1 (OPA1), a GTPase at the inner mitochondrial membrane involved in regulating mitochondrial fusion, stability, and energy output, is known to be crucial for neural development: Opa1 heterozygous mice show ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Abstract Evidence suggests that extracellular matrix molecules of perivascular basal laminae help orchestrate the molecular assemblies at the gliovascular interface. Specifically, laminin and agrin are thought to tether ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)Organotypic cultures from the ventral mesencephalon (VM) are widely used to model Parkinson’s disease (PD). In this method, neurotoxic compounds have traditionally been applied to the media to induce a uniform dopaminergic ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)Attention-deficit/hyperactivity disorder (ADHD), characterized by hyperactivity, impulsiveness and deficient sustained attention, is one of the most common and persistent behavioral disorders of childhood. ADHD is associated ...