Browsing Institutt for medisinske basalfag by Title
Now showing items 878-897 of 1342
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Introduction Obesity-susceptibility loci have been related to adiposity traits in adults and may affect body fat estimates in adolescence. There are indications that different sets of obesity-susceptibility loci influence ...
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Observed to expected or logistic regression to identify hospitals with high or low 30-day mortality? (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Introduction: A common quality indicator for monitoring and comparing hospitals is based on death within 30 days of admission. An important use is to determine whether a hospital has higher or lower mortality than other ...
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(Doctoral thesis / Doktoravhandling, 2013)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)Background High levels of stress among ambulance personnel have been attributed to the conditions of ambulance work. However, there is little research to support this notion, and it has been questioned ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Itch is an unpleasant symptom, affecting many dermatological patients. Studies investigating the occurrence and intensity of itch in dermatological patients often focus on a single skin disease and omit a control group ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Patients treated with allogeneic stem cell transplantation (allo-SCT) often develop ocular complications. To investigate the ocular findings in young long-term survivors after allo-SCT without TBI, we examined 96 patients ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)The LMNA gene encodes lamins A and C with key roles in nuclear structure, signaling, gene regulation, and genome integrity. Mutations in LMNA cause over 12 diseases (‘laminopathies’). Lamins A and C are identical for their ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)The relationship between collapsibility and confounding has been subject to an extensive and ongoing discussion in the methodological literature. We discuss two subtly different definitions of collapsibility, and show that ...
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(Doctoral thesis / Doktoravhandling, 2017)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)The comet assay has developed over the past 30 years and today, a variety of different DNA lesions and DNA repair can be measured by different versions of the assay (Collins, 2004). In the final step of the method, an image ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)There is a tendency to automatically use two-sided tests to assess the statistical significance of experimental results. Yet if a theory predicts the direction of an experimental outcome, or if for some practical (eg ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)LTX 315 is an oncolytic peptide with potent immunological properties. In the present study, we demonstrate that intratumoral treatment with LTX-315 resulted in a complete regression and systemic immune response in a rat ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background It is important that health-promoting efforts result in sustained behavioural changes, preferably throughout life. However, only a very few intervention studies evaluate long term follow up. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Optic atrophy 1 (OPA1) is the A-kinase anchoring protein targeting the pool of protein kinase A (PKA) responsible for perilipin 1 phosphorylation, a gatekeeper for lipolysis. However, the involvement of OPA1-bound PKA in ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)Organotypic cultures from the ventral mesencephalon (VM) are widely used to model Parkinson’s disease (PD). In this method, neurotoxic compounds have traditionally been applied to the media to induce a uniform dopaminergic ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)Attention-deficit/hyperactivity disorder (ADHD), characterized by hyperactivity, impulsiveness and deficient sustained attention, is one of the most common and persistent behavioral disorders of childhood. ADHD is associated ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)The acral skin contains arteriovenous anastomoses, which probably is the main part of skin microcirculation for blood flow adjustments and thermoregulation in the thermoneutral zone. The objective was to investigate if an ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)Background A subgroup of clinical trial subjects identified by baseline characteristics is a proper subgroup while a subgroup determined by post randomization events or measures is an improper subgroup. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background Procedures for the clinical assessment of acute poisoning by substances of abuse should identify patients in need of hospital admission and avoid hazardous discharges, while keeping the observation ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background The human genome contains a large amount of cis-regulatory DNA elements responsible for directing both spatial and temporal gene-expression patterns. Previous studies have shown that based on ...