Browsing Institutt for medisinske basalfag by Title
Now showing items 1005-1024 of 1961
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background Walking difficulties are common among pregnant women with pelvic girdle pain. This cross-sectional study investigated the influence of pelvic girdle pain, pregnancy and speed on spatiotemporal and trunk, pelvic ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background Glioblastoma (GBM) is the most common primary brain malignancy and confers a dismal prognosis. GBMs harbor glioblastoma-initiating cells (GICs) that drive tumorigenesis and contribute to therapeutic ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Motivation: Estimation of the hidden population structure is an important step in many genetic studies. Often the aim is also to identify which sequence locations are the most discriminative between groups of samples for ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)K+-channels of the Kv7/KCNQ-family hyperpolarize and stabilize excitable cells such as autonomic neurons and vascular smooth muscle cells (VSMC). Kv7 may therefore play a role in blood pressure (BP) homeostasis, and prevent ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)Background ADHD is currently defined as a cognitive/behavioral developmental disorder where all clinical criteria are behavioral. Overactivity, impulsiveness, and inattentiveness are presently regarded as ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Current studies addressing the influence of interleukin-33 or its receptor (IL-33R/ST2) on development of atopic dermatitis-like inflammation in mice have reported conflicting results. We compared the response in single- ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Cerebral malaria (CM), caused by Plasmodium falciparum infection, is a prevalent neurological disorder in the tropics. Most of the patients are children, typically with intractable seizures and high mortality. Current ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background Lactation has beneficial short term effects on maternal metabolic health, but the long term effects are less well known. Methods We ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)At the nuclear periphery, the genome is anchored to A- and B-type nuclear lamins in the form of heterochromatic lamina-associated domains. A-type lamins also associate with chromatin in the nuclear interior, away from the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)At the nuclear periphery, associations of chromatin with the nuclear lamina through lamina-associated domains (LADs) aid functional organization of the genome. We review the organization of LADs and provide evidence of LAD ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)The nuclear lamina contributes to the regulation of gene expression and to chromatin organization. Mutations in A-type nuclear lamins cause laminopathies, some of which are associated with a loss of heterochromatin at the ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)In non-Markov multi-state models, the traditional Aalen–Johansen (AJ) estimator for state transition probabilities is generally not valid. An alternative, suggested by Putter and Spitioni, is to analyse a subsample of the ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Hepatitis C virus (HCV) virions contain a subset of host liver cells proteome often composed of interesting virus-interacting factors. A proteomic analysis performed on double gradient-purified clinical HCV highlighted the ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Current treatment goals for familial hypercholesterolemia (FH) recommended by the European Atherosclerosis Society (EAS) are LDL-C ≤2.5 mmol/L (∼100 mg/dL) or ≤1.8 mmol/L (∼70 mg/dL) in very high-risk subjects. Objective The ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background: Fish consumption may have beneficial effects on metabolic syndrome (MetS); however, limited information of such associations exists. This study investigated possible associations between fish consumption and ...
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(Doctoral thesis / Doktoravhandling, 2017)Metabolic syndrome (MetS) is a cluster of risk factors for cardiovascular disease that include abdominal obesity, dyslipidemia, hyperglycemia and hypertension. Fish consumption may be a useful component when aiming to ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background Fish consumption may have a role in reducing the prevalence of metabolic syndrome (MetS). The aim of this study was to identify associations between fish consumption and MetS and its components, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Purpose To examine levels of oxidative DNA base damage and expression of selected genes and proteins related to DNA damage repair in human limbal epithelium engineered ex vivo. Methods Cells were expanded from limbal ...
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Leveraging multi-way interactions for systematic prediction of pre-clinical drug combination effects (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Abstract We present comboFM, a machine learning framework for predicting the responses of drug combinations in pre-clinical studies, such as those based on cell lines or patient-derived cells. comboFM models the cell ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Electrical extracellular recordings, i.e., recordings of the electrical potentials in the extracellular medium between cells, have been a main work-horse in electrophysiology for almost a century. The high-frequency part ...