Browsing Institutt for medisinske basalfag by Title
Now showing items 470-489 of 933
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background Glioblastoma (GBM) is the most common primary brain malignancy and confers a dismal prognosis. GBMs harbor glioblastoma-initiating cells (GICs) that drive tumorigenesis and contribute to therapeutic ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Motivation: Estimation of the hidden population structure is an important step in many genetic studies. Often the aim is also to identify which sequence locations are the most discriminative between groups of samples for ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)K+-channels of the Kv7/KCNQ-family hyperpolarize and stabilize excitable cells such as autonomic neurons and vascular smooth muscle cells (VSMC). Kv7 may therefore play a role in blood pressure (BP) homeostasis, and prevent ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)Background ADHD is currently defined as a cognitive/behavioral developmental disorder where all clinical criteria are behavioral. Overactivity, impulsiveness, and inattentiveness are presently regarded as ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Cerebral malaria (CM), caused by Plasmodium falciparum infection, is a prevalent neurological disorder in the tropics. Most of the patients are children, typically with intractable seizures and high mortality. Current ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background Lactation has beneficial short term effects on maternal metabolic health, but the long term effects are less well known. Methods We ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)At the nuclear periphery, the genome is anchored to A- and B-type nuclear lamins in the form of heterochromatic lamina-associated domains. A-type lamins also associate with chromatin in the nuclear interior, away from the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)The nuclear lamina contributes to the regulation of gene expression and to chromatin organization. Mutations in A-type nuclear lamins cause laminopathies, some of which are associated with a loss of heterochromatin at the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background: Fish consumption may have beneficial effects on metabolic syndrome (MetS); however, limited information of such associations exists. This study investigated possible associations between fish consumption and ...
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(Doctoral thesis / Doktoravhandling, 2017)Metabolic syndrome (MetS) is a cluster of risk factors for cardiovascular disease that include abdominal obesity, dyslipidemia, hyperglycemia and hypertension. Fish consumption may be a useful component when aiming to ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background Fish consumption may have a role in reducing the prevalence of metabolic syndrome (MetS). The aim of this study was to identify associations between fish consumption and MetS and its components, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Purpose To examine levels of oxidative DNA base damage and expression of selected genes and proteins related to DNA damage repair in human limbal epithelium engineered ex vivo. Methods Cells were expanded from limbal ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Electrical extracellular recordings, i.e., recordings of the electrical potentials in the extracellular medium between cells, have been a main work-horse in electrophysiology for almost a century. The high-frequency part ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)Background This study examined the relationship between life satisfaction among medical students and a basic model of personality, stress and coping. Previous studies have shown relatively high levels of ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background Despite many recent studies on burn-out and dissatisfaction among American medical doctors, less is known about doctors in the Scandinavian public health service. The aims of this study were to ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Crucian carp are unusual among vertebrates in surviving extended periods in the complete absence of molecular oxygen. During this time cardiac output is maintained though these mechanisms are not well understood. Using a ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background: To reduce colorectal cancer (CRC) mortality through population-based screening programmes using faecal tests, it is important that individuals continue to participate in the repeated rounds of screening. We ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Aims/hypothesis Activation of inflammatory pathways is involved in the pathogenesis of type 2 diabetes mellitus. On the basis of its role in vascular inflammation and in metabolic disorders, we hypothesised that the TNF ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Hip fractures have a high prevalence worldwide. Few studies have investigated whether fish consumption is associated with risk of hip fractures. The objective of the present study was to investigate the effect of fish ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biological pathways of regulation. ...