Browsing Institutt for molekylær biovitenskap by Title
Now showing items 82-101 of 121
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background Triage and interhospital transfer are central to trauma systems. Few studies have addressed transferred trauma patients. This study investigated transfers of variable distances to OUH (Oslo ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background Efficient expression systems exist for antibody (Ab) molecules, which allow for characterization of large numbers of individual Ab variants. In contrast, such expression systems have been lacking ...
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(Master thesis / Masteroppgave, 2009)Molecular evolution is a key strategy in the development of novel diagnostics and therapeutics. Libraries of mutant variants are generated and those with desired properties selected after screening. However, large scale ...
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(Master thesis / Hovedoppgave, 2004)In contrast to the mammalian major histocompatibility complex (MHC), where the MHC class I and class II loci reside in close vicinity to one another, the bony fishes have unlinked MHC class I and class II. Previous studies ...
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(Master thesis / Masteroppgave, 2005)The protein toxin ricin is found in the plant Ricinus communis, and is a useful tool in studies of intracellular traffic. It consists of an enzymatically active A chain and a B chain with lectin properties, joined together ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background FLASH is a huge nuclear protein involved in various cellular functions such as apoptosis signalling, NF-κB activation, S-phase regulation, processing of histone pre-mRNAs, and co-regulation of ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)The success of Fc-fusion bio-therapeutics has spurred the development of other Fc-fusion products for treating and/or vaccinating against a range of diseases. We describe a method to modulate their function by converting ...
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(Master thesis / Masteroppgave, 2009)Celiac disease is an autoimmune disease driven by an immune response to gluten peptides. The disease is strongly associated with the MHC class II molecule HLA-DQ2.5. The similar molecule HLA-DQ2.2 is not associated with ...
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(Doctoral thesis / Doktoravhandling, 2008)
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(Master thesis / Masteroppgave, 2011)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Although cloning and expression of T-cell Receptors (TcRs) has been performed for almost two decades, these procedures are still challenging. For example, the use of T-cell clones that have undergone limited expansion as ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)Background Trace or chromatogram files (raw data) are produced by automatic nucleic acid sequencing equipment or sequencers. Each file contains information which can be interpreted by specialised software ...
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(Doctoral thesis / Doktoravhandling, 2008)Exposure to particulate matter (PM) has been associated with increased cardiopulmonary morbidity and mortality, and inflammation has been suggested as a mechanistic link between PM exposure and adverse health effects. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Förster Resonance Energy Transfer , abbreviated FRET , is a fluorescence phenomenon, which can be used to study and map co-localizations and dynamics of co-localizations at nanometer precision on a light microscope. FRET ...
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(Doctoral thesis / Doktoravhandling, 2008)Doktorand Anders Øverbye har jobbet ved Institutt for kreftforskning ved Radiumhospitalet med sin avhandling innenfor de raskt voksende fagfeltene proteomikk og autofagi. Proteomikk innebærer utforskning av komplekse ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)Background Cyanopeptolins are nonribosomally produced heptapetides showing a highly variable composition. The cyanopeptolin synthetase operon has previously been investigated in three strains from the genera ...
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(Master thesis / Masteroppgave, 2012)
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Regulation of the gap junction protein connexin43 by members of the Nedd4 E3 ubiquitin ligase familyRestricted Access (Master thesis / Masteroppgave, 2010)
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(Master thesis / Masteroppgave, 2012)This study was carried out at the Department of Cell Biology at the Institute of Cancer Research at the Oslo University Hospital as a part of my Master’s degree in molecular biosciences at the University of Oslo. Our group ...
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(Master thesis / Masteroppgave, 2009)The human HMGA2 gene is located at chromosomal band 12q14-15. In normal cells it encodes for the HMGA2 protein (109 amino acids). HMGA2 is a transcription factor that binds to the AT rich sequences on DNA and thereby ...