Browsing Institutt for molekylær biovitenskap by Title
Now showing items 9-28 of 121
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)The cell cycle of the fission yeast, Schizosaccharomyces pombe, does not easily lend itself to analysis by flow cytometry, mainly because cells in G1 and G2 phase contain the same amount of DNA. This occurs because fission ...
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(Doctoral thesis / Doktoravhandling, 2008)In the endocytic pathway, many components are degraded. This is essential for cells in many ways, like uptake of nutrients, defense against pathogens, receptor downregulation, and antigen processing. In interphase, the ...
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Characterisation of the phosphatidylinositol-3-phosphate 5-kinase, Fab1, in Drosophila melanogaster (Master thesis / Hovedoppgave, 2004)Phosphoinositides play important roles in downregulation of growth factor receptors, such as the epidermal growth factor receptor (EGFR), through regulation of membrane transport and multivesicular body (MVB) biogenesis. ...
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(Master thesis / Hovedoppgave, 2004)A total of nine single-copy transgenic Arabidopsis thaliana lines displaying varying degrees of silencing of a nos promoter-nptII marker gene (encoding kanamycin-resistance) have been studied, with emphasis on two of these, ...
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(Doctoral thesis / Doktoravhandling, 2012)Most vertebrates die within minutes when exposed to anoxia (no oxygen). However, a few exceptions exist, and a champion among these is the crucian carp, which at low temperatures can survive several months in an active ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)Background When generating a genetically modified organism (GMO), the primary goal is to give a target organism one or several novel traits by using biotechnology techniques. A GMO will differ from its ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background Chlorophyll-binding proteins (CBPs) constitute a large family of proteins with diverse functions in both light-harvesting and photoprotection. The evolution of CBPs has been debated, especially ...
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(Master thesis / Hovedoppgave, 2005)The eukaryotic supergroup chromalveolates, as defined in the chromalveolate hypothesis, comprise the chromists (haptophytes, heterokonts and cryptophytes) and the alveolates (dinoflagellates, ciliates and apicomplexa). The ...
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(Master thesis / Hovedoppgave, 2004)For evolutionary and medical reasons bacterial classification is an important field within microbiology. Before Carl Woese introduced the use of ribosomal RNA sequences for phylogenetic comparison, bacterial classification ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2002)Background A method to evaluate and analyze the massive data generated by series of microarray experiments is of utmost importance to reveal the hidden patterns of gene expression. Because of the complexity ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)Background In order to gain new insights into the molecular mechanisms involved in prostate cancer, we performed array-based comparative genomic hybridization (aCGH) on a series of 46 primary prostate ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Human IgG3 displays the strongest effector functions of all IgG subclasses but has a short half-life for unresolved reasons. Here we show that IgG3 binds to IgG-salvage receptor (FcRn), but that FcRn-mediated transport and ...
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(Master thesis / Hovedoppgave, 2003)TCF11 is a regulatory transcription factor belonging to the CNC-bZIP family. The specific biological function of this protein is still unknown. However, knockout studies in mice have revealed its importance during embryo ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)The neonatal Fc receptor (FcRn) regulates the serum half-life of both IgG and albumin through a pH-dependent mechanism that involves salvage from intracellular degradation. Therapeutics and diagnostics built on IgG, Fc, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Phage display has been instrumental in discovery of novel binding peptides and folded domains for the past two decades. We recently reported a novel pIX phagemid display system that is characterized by a strong preference ...
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(Master thesis / Hovedoppgave, 2007)The Clamydomonas chloroplast rbcL gene encodes the large subunit of ribulose-bisphosphate carboxylase (RUBISCO). The 5`untranslated region (5`UTR) of the rbcL gene is crucial for its transcripts stability. Previous studies ...
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(Doctoral thesis / Doktoravhandling, 2009)This work, we believe, is a significant contribution to the development of molecular methods for the rapid detection of microorganism interacting with humans. Prevention, through the implementation of effective water ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)Background Soft tissue sarcoma (STS) diagnosis is challenging because of a multitude of histopathological subtypes, different genetic characteristics, and frequent intratumoral pleomorphism. One-third of ...
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(Master thesis / Masteroppgave, 2005)Det er vist at gallesubstanser er potente luktestimuli og induserer ulike typer adferdsmønstre hos fisk. Det er også flere egenskaper ved gallesaltene som gjør dem spesielt interessante i det akvatiske miljø som eksempel ...
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(Master thesis / Masteroppgave, 2005)Abstract Skeletal muscle fibre types are determined by the activity of motor neurons, hormones, stretch and probably cell lineage. The electrical activity of the motor neurons might, through an unknown pathway, influence ...