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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
Background
Frequent failure and severe side effects of current sarcoma therapy warrants new therapeutic approaches. The small-molecule MDM2 antagonist Nutlin-3a activates the p53 pathway and efficiently ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
Aldehyde dehydrogenase (ALDH) has recently been shown to be a marker of cancer stem-like cells (CSCs) across tumour types. The primary goals of this study were to investigate whether ALDH is expressed in liposarcomas, and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
Background
Conventional high-grade osteosarcoma is a primary malignant bone tumor, which is most prevalent in adolescence. Survival rates of osteosarcoma patients have not improved significantly in the last ...