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Polymorphic residues of HLA-DQ2.2 and HLA-DQ2.5 that affect CLIP presentation and stability 
Berg-Larsen, Axel (Master thesis / Masteroppgave, 2009)
Celiac disease is an autoimmune disease driven by an immune response to gluten peptides. The disease is strongly associated with the MHC class II molecule HLA-DQ2.5. The similar molecule HLA-DQ2.2 is not associated with ...
Direct Targeting of Invariant Chain to the MHC class II Loading Compartment Restricted Access
Kucera, Ana (Master thesis / Masteroppgave, 2009)
Identification of small molecule inhibitors of the transcription factor c-Myb through structure-based drug design and EMSA analysis Restricted Access
Martinez, Marcus Christoffer Rivertz (Master thesis / Masteroppgave, 2009)
Construction of a Heterologous Expression Vector for Plantaricin F, One of the Peptides Constituting the Two-Peptide Bacteriocin Plantaricin EF 
Jørgenrud, Benedicte Marie (Master thesis / Masteroppgave, 2009)
Certain species of lactic acid bacteria produce and secrete bacteriocins, which are ribosomally synthesized antimicrobial peptides. These peptides recognize and kill target cells by rendering their membrane permeable for ...
Det antimikrobielle peptidet Plantaricin A permeabiliserer lever- og nyreceller Restricted Access
Andersland, Kristin; Johansen, Guro Five (Master thesis / Masteroppgave, 2009)
Antimicrobial peptides are produced by nearly all organisms. Certain antimicrobial peptides from multicellular animals also kill a variety of tumour cells at concentrations not affecting normal eukaryotic cells. Recently, ...
Mapping the expression of anti-apoptotic proteins and evaluation of the therapeutic potential of TRAIL receptor antibodies in “close-to-patient” melanoma models. 
Hellenes, Tina (Master thesis / Masteroppgave, 2009)
Malignant melanoma is a very metastatic and therapy resistant disease, with few therapeutic options in advanced stages. An abnormal apoptosis pathway is considered to contribute substantially to the resistance observed in ...
PTM-crosstalk in c-Myb : Analysis of interdependence between posttranslational modifications in the negative regulatory domain of the oncoprotein c-Myb. Restricted Access
Vollsund, Pernille Hovde (Master thesis / Masteroppgave, 2009)
Heterolog ekspresjon av immunitetsproteinet til to-peptidbakteriosinet lactococcin G Restricted Access
Dybdahl, Linn (Master thesis / Masteroppgave, 2009)
Bakteriosiner er ribosomalt syntetiserte, antimikrobielle peptider som produseres av en rekke bakteriearter. Lactococcin G er et bakteriosin som består av to peptider, kalt α og β, og produseres av melkesyrebakterien ...
Cellular and sub-cellular localization of different N-methyl-D-aspartate receptor subunits in the hippocampal formation of mature and aged mice lacking the Neil3 gene Restricted Access
Regnell, Christine Elisabeth (Master thesis / Masteroppgave, 2009)
High levels of oxidative stress are a common aspect of most neurodegenerative disorders. Oxidative stress in the brain causes DNA lesions that are mainly repaired by the base excision repair (BER) pathway. The BER pathway ...
Functional Analysis of Kallikrein 4 in LNCaP cells Restricted Access
Zhang, Tianzhou (Master thesis / Masteroppgave, 2009)
Prostate cancer is one of the most frequently diagnosed cancers and second highest cause of death in patients who suffer from cancer in western countries. Much effort has been carried out to understand the molecular ...
Targeting Epidermal Growth Factor Receptor 2 in Carcinogenesis Restricted Access
Berger, Christian (Master thesis / Masteroppgave, 2009)
Nearly all human tissues express epidermal growth factor receptors(ErbBs)embedded in the plasma membrane. Four homologous ErbB proteins exert a pivotal function of transmitting proliferative signals by binding their cognate ...
Sulphide and Anoxia Tolerance in a Namibian Fish; How to Exploit a Hostile Environment 
Strandabø, Rønnaug (Master thesis / Masteroppgave, 2009)
The Benguela upwelling in Namibia and South Africa experienced an ecosystem collapse after overfishing in the 1960s and 1970s, and as several industrially important species became scarce, others grew abundant. One of these ...
The role of HMGA2 in mesenchymal biology 
Abrha, Biruk Luelseged (Master thesis / Masteroppgave, 2009)
The human HMGA2 gene is located at chromosomal band 12q14-15. In normal cells it encodes for the HMGA2 protein (109 amino acids). HMGA2 is a transcription factor that binds to the AT rich sequences on DNA and thereby ...
Construction of a vector system for functional verification of microRNA binding sites 
Solheim, Erle (Master thesis / Masteroppgave, 2009)
MicroRNAs (miRNAs) are a relatively newly discovered class of small endogenous non coding RNA molecules with important roles in cell function and cancer development. Mature miRNAs bind to complementary sequences of transcripts ...
Ligand-receptor matchmaking: Signaling of the IDL proteins through the LRR-RLKs of the HAESA family 
Kristiansen, Tonje (Master thesis / Masteroppgave, 2009)
Effects of social stress on neurogenesis related genes in rainbow trout 
Grcic, Sanja (Master thesis / Masteroppgave, 2009)
In mammals, adult neurogenesis is a restricted phenomenon, taking place in only two distinct areas of the brain, the subventricular zones and the hippocampus. The rate of adult neurogenesis can be regulated through a ...
Autofage organeller i rottehepatocytter : En studie av LC3-positive organeller etter separering med isotone tetthetsgradienter Restricted Access
Hagen, Linda Korseberg (Master thesis / Masteroppgave, 2009)
Autofagi er en intracellulær prosess eukaryote celler benytter til å bryte ned sitt eget cytoplasma ved langvarig sult eller proteinmangel, til negativ regulering av massevekst, og til spesifikk nedbrytning av ødelagte ...
Karakterisering av hNCU-G1 
Lystad, Alf Håkon (Master thesis / Masteroppgave, 2009)
Eskilds gruppe har vist at hNCU-G1 kan fungere som en ligandavhengig koaktivator for kjernereseptorer in vitro. Denne masteroppgaven bruker fluorescenskonfokalmikroskopi til videre å undersøke interaksjonen mellom hNCU-G1 ...
Effects of SMPX on skeletal muscle in adult mice 
Hansen, Einar Holm (Master thesis / Masteroppgave, 2009)
Mechanical factors are important in the regulation of muscle phenotype. Adaptation of structural and mechanical proteins to withstand increased load and cope with increased work is needed in a muscle exposed to mechanical ...
Ligand-receptor matchmaking: The IDA-HAE/HSL2 signaling system and the IDL and HSL relatives Restricted Access
Riiser, Even Sannes (Master thesis / Masteroppgave, 2009)
Until recently, most intercellular communication in plants has been explained by the signaling and perception of non-peptide plant hormones. It is, however, becoming increasingly clear that plant cell communication also ...
Characterisation of eukaryotic initiation factor 2 alpha in the fission yeast Schizosaccharomyces pombe 
Knutsen, Jon Halvor (Master thesis / Masteroppgave, 2009)
Our group has shown that ultraviolet (UV) irradiation of fission yeast cells in G1 phase induces a delayed entry into S phase. More recently, we found that the cell cycle delay is accompanied by a general depression of ...
Global transcriptional response after exposure of fission yeast cells to ultraviolet light 
Skjølberg, Henriette C; Fensgård, Øyvind; Nilsen, Hilde; Grallert, Beáta; Boye, Erik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)
Background In many cell types, including the fission yeast Schizosaccharomyces pombe, a set of checkpoints are induced by perturbations of the cell cycle or by DNA damage. Many of the checkpoint responses ...
Characterization of unknown genetic modifications using high throughput sequencing and computational subtraction 
Tengs, Torstein; Zhang, Haibo; Holst-Jensen, Arne; Bohlin, Jon; Butenko, Melinka A; Bråthen Kristoffersen, Anja; Opsahl Sorteberg, Hilde-Gunn; Berdal, Knut G (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)
Background When generating a genetically modified organism (GMO), the primary goal is to give a target organism one or several novel traits by using biotechnology techniques. A GMO will differ from its ...
A genome-wide analysis of nonribosomal peptide synthetase gene clusters and their peptides in a Planktothrix rubescens strain 
Rounge, Trine B; Rohrlack, Thomas; Nederbragt, Alexander J; Kristensen, Tom; Jakobsen, Kjetill S (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)
Background Cyanobacteria often produce several different oligopeptides, with unknown biological functions, by nonribosomal peptide synthetases (NRPS). Although some cyanobacterial NRPS gene cluster types ...
Up-regulation of uPARAP/Endo180 during culture activation of rat hepatic stellate cells and its presence in hepatic stellate cell lines from different species 
Mousavi, Seyed A; Fønhus, Marita S; Berg, Trond (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)
Background The urokinase plasminogen activator receptor associated protein (uPARAP)/Endo180 is a novel endocytic receptor that mediates collagen uptake and is implicated to play a role in physiological and ...
Identification of a High Affinity Fc gamma RIIA-binding Peptide That Distinguishes Fc gamma RIIA from Fc gamma RIIB and Exploits Fc gamma RIIA-mediated Phagocytosis and Degradation 
Berntzen, Gøril; Andersen, Jan Terje; Ustgård, Kristine; Ustgård, Kristine; Michaelsen, Terje Einar; Mousavi, Darbi Seyed Ali; Mousavi, Seyed Ali; Qian, Julie Dee; Qian, Julie Dee; Kristiansen, Per Eugen; Kristiansen, Per Eugen; Lauvrak, Vigdis; Sandlie, Inger (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)
FcγRIIA is a key activating receptor linking immune complex formation with cellular effector functions. FcγRIIA has 93% identity with an inhibitory receptor, FcγRIIB, which negatively regulates FcγRIIA. FcγRIIA is important ...
Development of microbiological molecular diagnostic techniques for the rapid screening and identification of selected human bacterial pathogens and indicators 
Anglès d Auriac, Marc B. (Doctoral thesis / Doktoravhandling, 2009)
This work, we believe, is a significant contribution to the development of molecular methods for the rapid detection of microorganism interacting with humans. Prevention, through the implementation of effective water ...
Endocytosis and retrograde transport of Shiga toxin and ricin 
Utskarpen, Audrun (Doctoral thesis / Doktoravhandling, 2009)
The plant toxin ricin and the bacterial toxin Shiga toxin are not only a threat to human health but may also be used in cancer treatment and to gain new insight into the mechanisms of intracellular transport. Ricin and ...
Periplasmic targeting of fluorobodies 
Øieren, Lise Mirja (Master thesis / Masteroppgave, 2009)
Molecular evolution is a key strategy in the development of novel diagnostics and therapeutics. Libraries of mutant variants are generated and those with desired properties selected after screening. However, large scale ...
PGC-1β's role in the regulation of adult mice muscle plasticity 
Staurseth, Julie (Master thesis / Masteroppgave, 2009)
Adult skeletal muscle fibers show an ability to undergo phenotypic alterations without cell death or regeneration in response to environmental changes. Important factors affecting the metabolic and contractile properties ...
Distribution of glucose uptake in hypoxic crucian carp tissues Restricted Access
Grøneng, Line Cecilie (Master thesis / Masteroppgave, 2009)
Glucose metabolism in crucian carp exposed to 3 days of hypoxia was studied using 14C-2-deoxyglucose (14C-DG) as a tracer. Four brain areas were investigated by autoradiography; telencephalon, optic tectum, cerebellum and ...
Exon-specific biomarkers in cancer : Experimental validation of exon microarray data from colorectal and testicular cancers 
Bakken, Anne Cathrine (Master thesis / Masteroppgave, 2009)
Crucian carp heart performance during anoxia and acidosis 
Larsen, Bent Collert (Master thesis / Masteroppgave, 2009)
Karuss (Carassius carassius L.) innehar den unike evnen blandt vertebrater å opprettholde hjerte kapasiteten på normoksisk nivå under langvarig eksponering til anoxia. Denne master oppgaven undersøker hypotesen om at dette ...
 
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Date Issued
2009 (33)
Document TypeMasteroppgave (26)Tidsskriftartikkel (5)Doktoravhandling (2)AuthorAbrha, Biruk Luelseged (1)Andersen, Jan Terje (1)Andersland, Kristin (1)Anglès d Auriac, Marc B. (1)Bakken, Anne Cathrine (1)... View MorePeer ReviewedPeer reviewed (5)
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