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Anti-carcinoembryonic Antigen Single-chain Variable Fragment Antibody Variants Bind Mouse and Human Neonatal Fc Receptor with Different Affinities That Reveal Distinct Cross-species Differences in Serum Half-life 
Andersen, Jan Terje; Foss, Stian; Kenanova, Vania E; Olafsen, Tove; Leikfoss, Ingvild Sørum; Roopenian, Derry C; Wu, Anna M; Sandlie, Inger (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
Serum half-life of IgG is controlled by the neonatal Fc receptor (FcRn) that interacts with the IgG Fc region and may be increased or decreased as a function of altered FcRn binding. Preclinical evaluations of modified ...
 
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Date Issued2012 (1)Document Type
Tidsskriftartikkel (1)
AuthorAndersen, Jan Terje (1)Foss, Stian (1)Kenanova, Vania E (1)Leikfoss, Ingvild Sørum (1)Olafsen, Tove (1)... View MorePeer ReviewedPeer reviewed (1)
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