Browsing Institutt for molekylær biovitenskap ( -2012) by Title
Now showing items 274-293 of 343
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(Master thesis / Masteroppgave, 2012)This study was carried out at the Department of Cell Biology at the Institute of Cancer Research at the Oslo University Hospital as a part of my Master’s degree in molecular biosciences at the University of Oslo. Our group ...
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(Master thesis / Masteroppgave, 2011)In addition to providing morphological support, the actin cytoskeleton is involved in cell motility, endocytosis and intracellular transport. Cytoskeletal interaction with the membrane is an essential part of these processes ...
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(Master thesis / Masteroppgave, 2009)The human HMGA2 gene is located at chromosomal band 12q14-15. In normal cells it encodes for the HMGA2 protein (109 amino acids). HMGA2 is a transcription factor that binds to the AT rich sequences on DNA and thereby ...
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(Master thesis / Masteroppgave, 2008)Animals store most excess energy as fat in specialized cells called adipocytes which form the major part of adipose tissue. Since obesity, which has reached epidemic proportions in the last decades, is the result of excess ...
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(Master thesis / Masteroppgave, 2010)The myogenic regulatory factors (MRFs) are a group of muscle specific transcription factors important during determination and differentiation of muscle fibers. In adult muscle two of the members, MyoD and myogenin, are ...
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Role of pro-inflammatory cytokines in persistent pain after disc herniation : nociceptive signaling and genetic susceptibilityRestricted Access (Master thesis / Masteroppgave, 2012)Low back pain and sciatica after disc herniation may be caused by mechanical compression of the nerve roots, but also by the release of inflammatory substances from nucleus pulposus (NP) of the herniated disc. In the present ...
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The Role of SNX8 in Retrograde Transport of Shiga Toxin : SNX8 facilitated transport of Shiga toxin is regulated by PKCdelta and p38alfaRestricted Access (Master thesis / Masteroppgave, 2010)Sorting nexin 8 (SNX8) belongs to the sorting nexin protein family. Members of this family are known to be involved in endocytosis and endosomal sorting. It was recently reported that SNX8 regulates retrograde transport ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)Background Lepeophtheirus salmonis is an ectoparasitic copepod feeding on skin, mucus and blood from salmonid hosts. Initial analysis of EST sequences from pre adult and adult stages of L. salmonis revealed ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2004)Background The transcription factor c-Myb is expressed in hematopoietic progenitor cells and other rapidly proliferating tissues, regulating genes important for proliferation, differentiation and survival. ...
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(Doctoral thesis / Doktoravhandling, 2012)
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Signalsystemer knyttet til TSH- og svellingstimulert taurineffluks i rottetyrocytter (FRTL-5-celler) (Master thesis / Masteroppgave, 2007)Sammendrag Taurin er den vanligste organiske osmolytten i de fleste dyrearter som er engasjert i volumregulering av celler. Tidligere studier har vist at både cellesvelling og TSH-stimulering øker taurineffluksen fra ...
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(Master thesis / Masteroppgave, 2012)Colorectal cancer (CRC) is a common type of cancer, and at present the TNM staging system is the only tool in routine clinical use for predicting patient outcome and making treatment decisions. Nuclear expression of the ...
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(Master thesis / Masteroppgave, 2006)Sequence-specific double-stranded small interfering RNAs (siRNAs) may effectively silence gene expression via a mechanism called RNA interference (RNAi). The focus of this study was mainly identification of active siRNA ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background The incidence of false positives is a potential problem in single-cell PCR experiments. This paper describes an optimized protocol for single-cell qPCR measurements in primary pituitary cell ...
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(Master thesis / Hovedoppgave, 2004)The disagreement between various immunoassays for the tumour marker carcinoembryonic antigen (CEA) is well known, and the discrepancies are explained by the co-measurement of the structurally related non-specific cross-reacting ...
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(Master thesis / Masteroppgave, 2005)Abstract The intention of this study was to identify and characterize signal pathways of the mesenchymal stem cell line hMSC-TERT which are being influenced by different mediators of inflammation. The purpose was also to ...
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(Master thesis / Masteroppgave, 2005)NUCKS-proteinet ble oppdaget i 1985 av Anne Carine Østvold og hennes medarbeidere ved Biokjemisk Institutt, Universitetet i Oslo. NUCKS genet er klonet og proteinet nøye karakterisert, men dets biologiske funksjon er ...
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(Master thesis / Masteroppgave, 2007)Colorectal cancer is one of the most common cancer types, and a leading cause of cancer-related deaths. Cases can be divided into two main molecular phenotypes: those with chromosomal instability (CIN) and those with ...
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Soluble and membrane bound peptide-MHC class II complexes as ligands for a specific T-cell receptor (Master thesis / Masteroppgave, 2007)Abstracts 1. Production of soluble peptide-MHC class II-Ig fusion proteins The aim of the study is to construct soluble variants of the murine MHC class II molecule I-Ed in complex with two tumor-specific peptides. ...
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(Master thesis / Masteroppgave, 2008)Epitelcellelinjen ”Madin-Darby canine kidney (MDCK)” er en velstudert polarisert cellelinje som danner tette cellelag med separate apikale og basolaterale membrandoméner. Proteoglykaner sorteres til både den apikale og den ...