Now showing items 1-14 of 14

  • Kaveh, Fatemeh; Baumbusch, Lars O; Nebdal, Daniel; Børresen-Dale, Anne-Lise; Lingjærde, Ole C; Edvardsen, Hege; Kristensen, Vessela N; Solvang, Hiroko K (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Background Detection and localization of genomic alterations and breakpoints are crucial in cancer research. The purpose of this study was to investigate, in a methodological and biological perspective, ...
  • Våtsveen, Thea K; Myhre, Marit R; Steen, Chloé B; Wälchli, Sébastien; Lingjærde, Ole C; Bai, Baoyan; Dillard, Pierre; Theodossiou, Theodossis A; Holien, Toril; Sundan, Anders; Inderberg, Else M; Smeland, Erlend B; Myklebust, June H; Oksvold, Morten P (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background Although chemo-immunotherapy has led to an improved overall survival for most B-cell lymphoma types, relapsed and refractory disease remains a challenge. The malaria drug artesunate has previously ...
  • Nilsen, Gro; Liestøl, Knut; Loo, Peter V; Moen Vollan, Hans K; Eide, Marianne B; Rueda, Oscar M; Chin, Suet-Feung; Russell, Roslin; Baumbusch, Lars O; Caldas, Carlos; Børresen-Dale, Anne-Lise; Lingjærde, Ole C (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
    Background Cancer progression is associated with genomic instability and an accumulation of gains and losses of DNA. The growing variety of tools for measuring genomic copy numbers, including various types ...
  • Haakensen, Vilde D; Biong, Margarethe; Lingjærde, Ole C; Holmen, Marit M; Frantzen, Jan O; Chen, Ying; Navjord, Dina; Romundstad, Linda; Lüders, Torben; Bukholm, Ida K; Solvang, Hiroko K; Kristensen, Vessela N; Ursin, Giske; Børresen-Dale, Anne-Lise; Helland, Åslaug (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
    Introduction Mammographic density (MD), as assessed from film screen mammograms, is determined by the relative content of adipose, connective and epithelial tissue in the female breast. In epidemiological ...
  • Aure, Miriam R; Jernström, Sandra; Krohn, Marit; Vollan, Hans K M; Due, Eldri U; Rødland, Einar; Kåresen, Rolf; Ram, Prahlad; Lu, Yiling; Mills, Gordon B; Sahlberg, Kristine K; Børresen-Dale, Anne-Lise; Lingjærde, Ole C; Kristensen, Vessela N (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Background The role played by microRNAs in the deregulation of protein expression in breast cancer is only partly understood. To gain insight, the combined effect of microRNA and mRNA expression on protein ...
  • Aure, Miriam R; Vitelli, Valeria; Jernström, Sandra; Kumar, Surendra; Krohn, Marit; Due, Eldri U; Haukaas, Tonje H; Leivonen, Suvi-Katri; Vollan, Hans K M; Lüders, Torben; Rødland, Einar; Vaske, Charles J; Zhao, Wei; Møller, Elen K; Nord, Silje; Giskeødegård, Guro F; Bathen, Tone F; Caldas, Carlos; Tramm, Trine; Alsner, Jan; Overgaard, Jens; Geisler, Jürgen; Bukholm, Ida R K; Naume, Bjørn; Schlichting, Ellen; Sauer, Torill; Mills, Gordon B; Kåresen, Rolf; Mælandsmo, Gunhild M; Lingjærde, Ole C; Frigessi, Arnoldo; Kristensen, Vessela N; Børresen-Dale, Anne-Lise; Sahlberg, Kristine K (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background Breast cancer is a heterogeneous disease at the clinical and molecular level. In this study we integrate classifications extracted from five different molecular levels in order to identify ...
  • Solvang, Hiroko K; Lingjærde, Ole C; Frigessi, Arnoldo; Børresen-Dale, Anne-Lise; Kristensen, Vessela N (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biological pathways of regulation. ...
  • Borgan, Eldrid; Sitter, Beathe; Lingjærde, Ole C; Johnsen, Hilde; Lundgren, Steinar; Bathen, Tone F; Sørlie, Therese; Børresen-Dale, Anne-Lise; Gribbestad, Ingrid S (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
    Background Combining gene expression microarrays and high resolution magic angle spinning magnetic resonance spectroscopy (HR MAS MRS) of the same tissue samples enables comparison of the transcriptional ...
  • Haukaas, Tonje H; Euceda, Leslie R; Giskeødegård, Guro F; Lamichhane, Santosh; Krohn, Marit; Jernström, Sandra; Aure, Miriam R; Lingjærde, Ole C; Schlichting, Ellen; Garred, Øystein; Due, Eldri U; Mills, Gordon B; Sahlberg, Kristine K; Børresen-Dale, Anne-Lise; Bathen, Tone F (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Background The heterogeneous biology of breast cancer leads to high diversity in prognosis and response to treatment, even for patients with similar clinical diagnosis, histology, and stage of disease. ...
  • Kristensen, Vessela N; Tsalenko, Anya; Geisler, Jurgen; Faldaas, Anne; Grenaker, Grethe I; Lingjærde, Ole C; Fjeldstad, Ståle; Yakhini, Zohar; Lønning, Per E; Børresen-Dale, Anne-Lise (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
    Background Complex traits, which are under the influence of multiple and possibly interacting genes, have become a subject of new statistical methodological research. One of the greatest challenges facing ...
  • Zhao, Xi; Rødland, Einar A; Sørlie, Therese; Vollan, Hans K M; Russnes, Hege G; Kristensen, Vessela N; Lingjærde, Ole C; Børresen-Dale, Anne-Lise (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
  • Russnes, Hege G; Lønning, Per E; Børresen-Dale, Anne-Lise; Lingjærde, Ole C (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    The availability of large amounts of molecular data of unprecedented depth and width has instigated new paths of interdisciplinary activity in cancer research. Translation of such information to allow its optimal use in ...
  • Höglander, Elen K; Nord, Silje; Wedge, David C; Lingjærde, Ole C; Silwal-Pandit, Laxmi; Gythfeldt, Hedda v; Vollan, Hans K M; Fleischer, Thomas; Krohn, Marit; Schlitchting, Ellen; Borgen, Elin; Garred, Øystein; Holmen, Marit M; Wist, Erik; Naume, Bjørn; Van Loo, Peter; Børresen-Dale, Anne-Lise; Engebraaten, Olav; Kristensen, Vessela (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background Chemotherapeutic agents such as anthracyclines and taxanes are commonly used in the neoadjuvant setting. Bevacizumab is an antibody which binds to vascular endothelial growth factor A (VEGFA) ...
  • Tinholt, Mari; Vollan, Hans K M; Sahlberg, Kristine K; Jernström, Sandra; Kaveh, Fatemeh; Lingjærde, Ole C; Kåresen, Rolf; Sauer, Torill; Kristensen, Vessela; Børresen-Dale, Anne-Lise; Sandset, Per M; Iversen, Nina (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Introduction Hypercoagulability in malignancy increases the risk of thrombosis, but is also involved in cancer progression. Experimental studies suggest that tissue factor (TF) and tissue factor pathway ...