Browsing by Author "Xavier, Ramnik J."

Now showing items 1-2 of 2

  • Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease 
    Goel, Gautam; Tye-Din, Jason A.; Qiao, Shuo Wang; Russell, Amy K.; Mayassi, Toufic; Ciszewski, Cezary; Sarna, Vikas Kumar; Wang, Suyue; Goldstein, Kaela E.; Dzuris, John L.; Williams, Leslie J.; Xavier, Ramnik J.; Lundin, Knut Erik Aslaksen; Jabri, Bana; Sollid, Ludvig Magne; Anderson, Robert P. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Celiac disease (CeD), caused by immune reactions to cereal gluten, is treated with gluten -elimination diets. Within hours of gluten exposure, either perorally or extraorally by intradermal injection, treated patients ...
  • Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies 
    Goel, Gautam; King, Tim; Daveson, A. James; Andrews, Jane M.; Krishnarajah, Janakan; Krause, Richard; Brown, Gregor J.E.; Fogel, Ronald; Barish, Charles F.; Epstein, Roger; Kinney, Timothy P.; Miner, Philip B.; Tye-Din, Jason A.; Girardin, Adam; Taavela, Juha; Popp, Alina; Sidney, John; Mäki, Markku; Goldstein, Kaela E.; Griffin, Patrick H.; Wang, Suyue; Dzuris, John L.; Williams, Leslie J.; Sette, Alessandro; Xavier, Ramnik J.; Sollid, Ludvig Magne; Jabri, Bana; Anderson, Robert P. (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    Background: A gluten-free diet is the only means to manage coeliac disease, a permanent immune intolerance to gluten. We developed a therapeutic vaccine, Nexvax2, designed to treat coeliac disease. Nexvax2 is an adjuvant-free ...