Browsing by Author "Haugen, Mads H"

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  • Cystatin E/M suppresses legumain activity and invasion of human melanoma 
    Briggs, Jon J; Haugen, Mads H; Johansen, Harald T; Riker, Adam I; Abrahamson, Magnus; Fodstad, Øystein; Mælandsmo, Gunhild M; Solberg, Rigmor (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
    Background High activity of cysteine proteases such as legumain and the cathepsins have been shown to facilitate growth and invasion of a variety of tumor types. In breast cancer, several recent studies ...
  • Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer 
    Grinde, Maria T; Hilmarsdottir, Bylgja; Tunset, Hanna M; Henriksen, Ida M; Kim, Jana; Haugen, Mads H; Rye, Morten B; Mælandsmo, Gunhild M; Moestue, Siver A (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Introduction Glutaminase inhibitors target cancer cells by blocking the conversion of glutamine to glutamate, thereby potentially interfering with anaplerosis and synthesis of amino acids and glutathione. ...