Browsing by Title
Now showing items 84957-84976 of 97172
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(Journal article / Tidsskriftartikkel / SubmittedVersion, 2019)Background Activated leukocytes may contribute to the development and progression of heart failure (HF). We investigated the predictive value of circulating levels of stable and readily detectable markers reflecting ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Aquaporin-4 (AQP4)-specific Th17 cells are thought to have a central role in neuromyelitis optica (NMO) pathogenesis. When modeling NMO, only AQP4-reactive Th17 cells from AQP4-deficient (AQP4−/−), but not wild-type (WT) ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)T lymphocytes (T cells) are divided into two functionally different subgroups the CD4+ T helper cells (Th) and the CD8+ cytotoxic T lymphocytes (CTL). Adequate CD4 and CD8 T cell activation to proliferation, clonal expansion ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)An individual's T cell repertoire is skewed towards some specificities as a result of past antigen exposure and subsequent clonal expansion. Identifying T cell receptor signatures associated with a disease is challenging ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Abstract Background Colorectal liver metastasis (CLM) is a leading cause of colorectal cancer mortality, and the response to immune checkpoint inhibition (ICI) in microsatellite-stable CRC ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2001)Type-B T cells raised against the immunodominant peptide in hen egg lysozyme (HEL(48-62)) do not respond to whole lysozyme, and this has been thought to indicate that peptide can bind to I-A(k) in different conformations. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Mycobacterium tuberculosis (Mtb) is particularly challenging for the immune system being an intracellular pathogen, and a variety of T cell subpopulations are activated by the host defence mechanism. In this study, we ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Immune responses in people with multiple sclerosis (pwMS) receiving disease-modifying therapies (DMTs) have been of significant interest throughout the COVID-19 pandemic. Lymphocyte-targeting immunotherapies, including ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background The Lck and Src binding adaptor protein TSAd (T cell specific adaptor) regulates actin polymerization in T cells and endothelial cells. The molecular details as to how TSAd regulates this process ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)Purpose: T cells infiltrating follicular lymphoma (FL) tumors are considered dysfunctional, yet the optimal target for immune checkpoint blockade is unknown. Characterizing coinhibitory receptor expression patterns and ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Abstract Unlike chimeric antigen receptors, T-cell receptors (TCRs) can recognize intracellular targets presented on human leukocyte antigen (HLA) molecules. Here we demonstrate that T cells expressing TCRs specific for ...
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(Master thesis / Masteroppgave, 2021)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Abstract In the fetus, the cardiac neural crest gives rise to both the thymus and the conotruncus of the heart. In newborn screening for severe T-cell lymphopenia neonates with congenital heart defects may be detected. In ...
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(Doctoral thesis / Doktoravhandling, 2017)
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(Master thesis / Masteroppgave, 2011)Bakgrunn: T-celle spesifikt adapterprotein (TSAd), som blir kodet av genet SH2D2A, er et protein som er involvert i protein-protein interaksjoner i signaloverføing som skjær når T-cellen aktiveres. TSAd er uttrykt i T-celler, ...
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(Master thesis / Prosjektoppgave, 2005)The SH2D2A gene codes for a protein which was named T cell specific adapter protein (TSAd) by the group who cloned it in 1997. The gene is located to 1q21, a region where several immunoregulative genes are situated. The ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Chronic lymphocytic leukaemia (CLL) is characterised by malignant mature-like B cells. Supportive to CLL cell survival is chronic B-cell receptor (BCR) signalling; however, emerging evidence demonstrates CLL cells proliferate ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Seismic reflection data along volcanic passive margins frequently provide imaging of strong and laterally continuous reflections in the middle and lower crust. We have completed a detailed 2‐D seismic interpretation of the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background During the last 30 years, the median sample size of research studies published in high-impact medical journals has increased manyfold, while the use of non-parametric tests has increased at the ...
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(Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)Review of "T. Douglas Price: Ancient Scandinavia. An Archaeological History from the First Humans to the Vikings" and more general discussion of curriculum in archaeological training